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  • © 2006

RNA Towards Medicine

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 173)

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Table of contents (23 chapters)

  1. Front Matter

    Pages I-XI
  2. Regulatory RNAs as Mediators of Virulence Gene Expression in Bacteria

    • T. Geissmann, M. Possedko, E. Huntzinger, P. Fechter, C. Ehresmann, P. Romby
    Pages 9-43
  3. Regulatory RNAs in Mammals

    • M. Szymański, J. Barciszewski
    Pages 45-72
  4. Aminoglycoside Interactions with RNAs and Nucleases

    • L.A. Kirsebom, A. Virtanen, N.E. Mikkelsen
    Pages 73-96
  5. High-Throughput RNA Interference in Functional Genomics

    • M. Janitz, D. Vanhecke, H. Lehrach
    Pages 97-104
  6. Antiviral Applications of RNAi

    • K.V. Morris, J.J. Rossi
    Pages 105-116
  7. RNA Interference: Its Use as Antiviral Therapy

    • J. Haasnoot, B. Berkhout
    Pages 117-150
  8. Gene Silencing of Virus Replication by RNA Interference

    • N. Miyano-Kurosaki, H. Takaku
    Pages 151-171
  9. Progress in the Development of Nucleic Acid Therapeutics

    • A. Kalota, V.R. Dondeti, A.M. Gewirtz
    Pages 173-196
  10. Strategies to Identify Potential Therapeutic Target Sites in RNA

    • M. Lützelberger, J. Kjems
    Pages 243-259
  11. Oligonucleotide-Based Antiviral Strategies

    • S. Schubert, J. Kurreck
    Pages 261-287
  12. RNA Aptamers Directed Against Oligosaccharides

    • M. Sprinzl, M. Milovnikova, C.S. Voertler
    Pages 327-340
  13. Application of Aptamers in Therapeutics and for Small-Molecule Detection

    • M. Menger, J. Glökler, M. Rimmele
    Pages 359-373
  14. RNA Aptamers as Potential Pharmaceuticals Against Infections with African Trypanosomes

    • H.U. Göringer, M. Homann, M. Zacharias, A. Adler
    Pages 375-393

About this book

Developments over the past few years have revealed the remarkable versatility of RNA in any compartment of the cell, tasks that had been thought to be exclusively in the realm of proteins and even beyond. The chapters in this book written by leading investigators in the field provide insight into various promising avenues where RNA and nucleic acid derivatives including antisense RNAs, such as siRNA, miRNAs, amplification/selection (SELEX) generated aptamers as well as ribozymes are at the threshold of impacting medicine.

Editors and Affiliations

  • Institute of Chemistry/Biochemistry, Free University Berlin, Berlin, Germany

    Volker Erdmann

  • Institute of Bioorganic Chemistry, Polish Academy of Scienes, Poznan, Poland

    Jan Barciszewski

  • Institute of Experimental Pathology, Molecular Neurobiology (ZMBE), University of Münster, Münster, Germany

    Jürgen Brosius

Bibliographic Information

Buy it now

Buying options

eBook USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access