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  • Conference proceedings
  • © 2005

Animal Models of T Cell-Mediated Skin Diseases

Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 50)

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Table of contents (16 papers)

  1. Front Matter

    Pages I-XIII
  2. Making Gene-Modified Mice

    • M. Pasparakis
    Pages 1-26
  3. Animal Models of Experimental Asthma

    • M. Wegmann, H. Renz
    Pages 69-87
  4. Models of Rheumatoid Arthritis

    • R. O. Williams
    Pages 89-117
  5. Animal Models of Inflammatory Bowel Diseases

    • M. F. Neurath
    Pages 119-132
  6. Murine Models of Atopic Dermatitis

    • T. Brzoska, T. A. Luger
    Pages 133-166
  7. T-Cell Receptor Transgenic Models of Inflammatory Disorders: Relevance for Atopic Dermatitis?

    • U. Niesner, F. Hardung, A. Scheffold, A. Radbruch
    Pages 175-191
  8. Acute and Chronic Models of Allergic Contact Dermatitis: Advantages and Limitations

    • T. M. Zollner, F. H. Igney, K. Asadullah
    Pages 255-275
  9. Back Matter

    Pages 293-296

About this book

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases". Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.

Editors and Affiliations

  • Corporate Research Business Area Dermatology, Schering AG, Berlin, Germany

    T. Zollner, K. Asadullah

  • Department of Clinical Chemistry and Molecular Diagnostics, Hospital of the Philipps-University, Marburg, Germany

    H. Renz

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access