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Nisoldipine 1987

  • Conference proceedings
  • © 1987

Overview

Editors:
  1. P. G. Hugenholtz

    1. Medical Faculty, Thoraxcenter, Erasmus University Rotterdam, Rotterdam, The Netherlands

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  2. J. Meyer

    1. II. Med. Klinik und Poliklinik, Klinikum der Universität Mainz, Mainz, Germany

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (54 papers)

  1. Front Matter

    Pages I-XX
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  2. Experimental and Clinical Pharmacology

    1. Front Matter

      Pages 1-1
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    2. Experimental Pharmacology of Nisoldipine: Perspectives from Long-Term Studies

      • S. Kazda, J.-P. Stasch, Claudia Hirth
      Pages 3-12

    3. Membrane Potential and Nisoldipine Block of Calcium Channels in the Heart: Interactions with Channel Gating

      • R. S. Kass, J. P. Arena, R. S. Wiener
      Pages 13-26

    4. Review of Nisoldipine Binding Studies

      • R. A. Janis, A. V. Shrikhande, R. Greguski, M. Pan, A. Scriabine
      Pages 27-35

    5. Comparison of Nifedipine and Nisoldipine on Human Arteries and Human Cardiac Tissues In Vitro

      • T. Godfraind, C. Eglème, M. Finet, B. Debande, P. Jaumin
      Pages 36-44

    6. Effect of Prolonged Treatment with Nisoldipine on Cholesterol Deposition and Cardiac Noradrenaline Reserves: A Comparative Study

      • W. G. Nayler, S. Panagiotopoulos, W. J. Sturrock
      Pages 45-58

    7. Pharmacokinetics of Nisoldipine

      • G. Ahr, W. Wingender, J. Kuhlmann
      Pages 59-66

    8. Plasma Level-Effect Relationships for some Acute Cardiovascular Effects of Nisoldipine and Other Dihydropyridine Calcium Channel Antagonists

      • K.-H. Graefe, R. Ziegler, W. Wingender, K.-D. Rämsch, G. Ahr, H. Schmitz
      Pages 67-75

    9. Pharmacokinetics and Haemodynamic Effects of Nisoldipine in Patients with Liver Cirrhosis

      • J. van Harten, P. van Brummelen, J. H. P. Wilson, D. D. Breimer
      Pages 76-79

    10. Steady-State Pharmacokinetics of Nisoldipine in Patients with Liver Disease

      • R. Joeres, G. Ahr, G. Hofstetter, H. Klinker, E. Richter
      Pages 80-84

    11. Biotransformation of Nisoldipine in Man

      • D. Scherling, G. Ahr, W. Karl
      Pages 85-88

    12. Effect of Nisoldipine on Electrophysiological Parameters in Man

      • H. H. Klein, H. Kreuzer
      Pages 89-93

    13. Chairman’s Analysis

      • W. Klaus
      Pages 94-95

  3. Effects on Coronary Arteries: Role of Vasomotor Tone

    1. Front Matter

      Pages 97-97
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    2. Effect of Nisoldipine on Variant Angina

      • H. Yasue
      Pages 99-102

    3. Hemodynamic Effects of Intravenous Nisoldipine

      • K. J. Beatt, P. W. Serruys, A. Soward, P. J. de Feyter, P. G. Hugenholtz
      Pages 103-108

    4. Direct Cardiac and Peripheral Vascular Effects of Intracoronary Nisoldipine

      • M. Schartl, C. Heidelmeyer, F. C. Dougherty, H. Schmutzler
      Pages 109-114

    5. Antianginal Efficacy of Nisoldipine in Patients with Unstable Angina Pectoris: Evaluation on Holter ECG

      • F. Otsu, H. Kishida
      Pages 115-122

    6. Attenuation by Nisoldipine of the Abnormal Response to Cold Pressor Stimulation in Patients with Ischaemia and Normal Coronary Arteries

      • S. O. Banim, J. L. Caplin, J. C. O’Keefe, D. S. Dymond
      Pages 123-127
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Keywords

About this book

This book, the first to provide a comprehensive overview of all studies so far carried out with this second-generation calcium entry blocker, Nisoldipine, is the fruit of a- day conference. In the first part the essential data on its experimental and clinical pharmacology are summarised by outstanding research workers in this field. The second part contains work concerning the major action of the drug, namely its effect in reducing vasomotor tone. The third part deals with intravenous or oral administration. From these data a clear profile develops, which is effective in angina pectoris of various forms and in cardiac ischaemia, both the clinically evident and the silent forms. Additionally, exploratory data in the area of cardiac failure are presented. As several contributors are based on material presented as a poster they do not contain a reference list. This book is highly recommended for all those investigators and clinicians who are researching for the optimal calcium entry blocker.

Editors and Affiliations

  • Medical Faculty, Thoraxcenter, Erasmus University Rotterdam, Rotterdam, The Netherlands

    P. G. Hugenholtz

  • II. Med. Klinik und Poliklinik, Klinikum der Universität Mainz, Mainz, Germany

    J. Meyer

Bibliographic Information

  • Book Title: Nisoldipine 1987

  • Editors: P. G. Hugenholtz, J. Meyer

  • DOI: https://doi.org/10.1007/978-3-642-73010-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1987

  • Softcover ISBN: 978-3-540-18394-5Due: 23 November 1987

  • eBook ISBN: 978-3-642-73010-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XX, 348

  • Number of Illustrations: 12 b/w illustrations

  • Topics: Pharmacology/Toxicology, Cardiology

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