Pathology of Rheumatic Diseases

1. Front Matter

   Pages I-XI

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2. The History of Rheumatic Diseases

   • Hans Georg Fassbender

   Pages 1-5

3. Components of Connective Tissue

   • Hans Georg Fassbender

   Pages 7-13

4. Reactions

   • Hans Georg Fassbender

   Pages 15-18

5. Rheumatic Fever

   • Hans Georg Fassbender

   Pages 19-78

6. Rheumatoid Arthritis

   • Hans Georg Fassbender

   Pages 79-210

7. Juvenile Rheumatoid Arthritis and Still’s Disease

   • Hans Georg Fassbender

   Pages 211-215

8. Sjögren’s Syndrome

   • Hans Georg Fassbender

   Pages 217-220

9. Ankylosing Spondylitis

   • Hans Georg Fassbender

   Pages 221-244

10. Psoriatic Arthritis

    • Hans Georg Fassbender

    Pages 245-258

11. Gout

    • Hans Georg Fassbender

    Pages 259-273

12. Chondrocalcinosis

    • Hans Georg Fassbender

    Pages 275-278

13. Osteo-Arthritis

    • Hans Georg Fassbender

    Pages 279-301

14. Non-Articular Rheumatism

    • Hans Georg Fassbender

    Pages 303-314

15. Experimental Arthritis

    • Hans Georg Fassbender

    Pages 315-326

16. References

    • Hans Georg Fassbender

    Pages 327-338

17. Back Matter

    Pages 339-356

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Pathology is no longer the" dead science" it was reputed to be a few decades ago. The famous Canadian pathologist, William Boyd, expressed the newer attitude aptly when he stated that pathology should no longer be concerned simply with describing the" WHAT" of disease, but must be increasingly con­ cerned with the "HOW" and the "WHY". By this he implied that the preoccupa­ tion of the usual student of disease in the architecture of diseased tissues and descriptions of participating cells, their staining characteristics, etc. , must give way to study and understanding of the dynamics of each disease process, the pathogenetic mechanisms producing the changes in body tissues. This study is not limited simply to etiologic factors and portals of entry to the site of the lesion, but includes the physical and chemical factors involved, the variations of host response conditioned by immunologic reactions of differing intensities, enzymatic excesses or deficiencies, and a host of other variables of little known character such as the prostaglandins which definitely affect the disease process. No longer is the pathologist one who looks at sections of diseased tissue merely for differentiation of disease, but truly a pathologist studies disease.

• Arthritis
• diseases
• pathology
• rheumatic diseases
• rheumatism
• rheumatoid arthritis

• Zentrums für Rheuma-Pathologie, Universität Mainz, Mainz, FR Germany

  Hans Georg Fassbender

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