Overview
- Each volume of Topics in Organometallic Chemistry provides the broad scientific readership with comprehensive summary and critical overview of a topic in organometallic chemistry
- Research in this rapidly developing transdisciplinary field is having profound influence on other areas of scientific investigation, ranging from catalytic organic synthesis to biology, medicine and material science
Part of the book series: Topics in Organometallic Chemistry (TOPORGAN, volume 6)
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Table of contents (10 chapters)
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Front Matter
Keywords
About this book
The design of efficient syntheses of medicinal agents is one of the prime goals of the process chemist in the pharmaceutical industry. The expanding list of metal-mediated reactions has had a major impact on this endeavor over the last two decades. This volume will highlight some of the areas of organometallic chemistry that have played a particularly important role in development. The chapters are written by chemists who work in the process groups of major pharmaceutical companies and fine chemical manufacturers. Having demonstrated the power of organometallics in their processes the authors herein expand upon their experiences with examples from the literature as reported by process groups within the industry. The chapters are organized either by the application of a particular metal or reaction class. Removal of the residual metal(s) from the isolated active pharmaceutical ingredient (API) is key to the release of the material for human consumption, and hence, is reviewed here as well. This volume of Topics in Organometallic Chemistry is presented to offer a representative cross section of organometallic applications in the pharmaceutical industry as well as to give an appreciation for the creativity possible in process chemistry.
Reviews
From the reviews:
From "Angewandte Chemie", Vol. 44, Issue 3, pp. 359-360
"Within the book’s 295 pages, consisting of ten important and well-chosen articles, every reader concerned with the subject is sure to quickly find material relevant to his or her special interests."
"The use of organometallic compounds in chemical process development in the pharmaceutical, agricultural, and fine chemical industries is the focus of the volume. … Overall, the quality and layout of the drawings are quite good, which gives the book high readability. There is also a cumulative author index … . it is one of growing importance and visibility in the organic chemistry community. … the information and underlying message would be quite beneficial for academicians to experience and appreciate." (Kim Albizati, Journal of the American Chemical Society, Vol. 127 (6), 2005)
"It is impossible to imagine synthetic work without the help of organometallic transformations. …The individual chapters of the book can be regarded as giving a snapshot of the present state of progress in this technology. … every reader concerned with the subject is sure to quickly find material relevant to his or her special interests. … it should certainly be available in the libraries of companies that are concerned with this type of chemistry. It can also serve as a quick source of useful information for university teachers … ." (Martin Bröring, Angewandte Chemie International Edition, Vol. 44 (3), 2005)
Editors and Affiliations
Bibliographic Information
Book Title: Organometallics in Process Chemistry
Editors: Rob Larsen
Series Title: Topics in Organometallic Chemistry
DOI: https://doi.org/10.1007/b11774
Publisher: Springer Berlin, Heidelberg
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eBook Packages: Springer Book Archive
Copyright Information: Springer-Verlag Berlin Heidelberg 2004
Hardcover ISBN: 978-3-540-01603-8Published: 15 June 2004
Softcover ISBN: 978-3-642-05687-1Published: 21 October 2010
eBook ISBN: 978-3-540-36966-0Published: 01 June 2004
Series ISSN: 1436-6002
Series E-ISSN: 1616-8534
Edition Number: 1
Number of Pages: IX, 286
Topics: Organometallic Chemistry, Catalysis, Inorganic Chemistry, Medicinal Chemistry, Industrial Chemistry/Chemical Engineering