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Antiseptic Stewardship

Biocide Resistance and Clinical Implications

  • Book
  • © 2018

Overview

Authors:
  1. Günter Kampf

    1. Institute of Hygiene and Environmental Medicine, University of Greifswald, Greifswald, Germany

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  • Provides a comprehensive literature overview on efficacy, adaptation, acquired resistance and cross-resistance for various commonly used antiseptic agents
  • Focus on the potential of antiseptics to enhance cross-resistance to antibiotics where multi-resistance has become a major global threat
  • Offers practical guidance for academics, professionals and others to make informed decisions on various antiseptic agents in different types of products (e.g. alcohol-based hand rubs, skin antiseptics etc.)
  • Helps to reduce unnecessary bacterial or fungal selection pressure so that the efficacy of useful antiseptics is not impaired in the future

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xli
    Download chapter PDF

  2. Introduction

    • Günter Kampf
    Pages 1-7

  3. Ethanol

    • Günter Kampf
    Pages 9-35

  4. Propan-1-ol

    • Günter Kampf
    Pages 37-46

  5. Propan-2-ol

    • Günter Kampf
    Pages 47-61

  6. Peracetic Acid

    • Günter Kampf
    Pages 63-98

  7. Hydrogen Peroxide

    • Günter Kampf
    Pages 99-130

  8. Glutaraldehyde

    • Günter Kampf
    Pages 131-160

  9. Sodium Hypochlorite

    • Günter Kampf
    Pages 161-210

  10. Triclosan

    • Günter Kampf
    Pages 211-258

  11. Benzalkonium Chloride

    • Günter Kampf
    Pages 259-370

  12. Didecyldimethylammonium Chloride

    • Günter Kampf
    Pages 371-394

  13. Polihexanide

    • Günter Kampf
    Pages 395-427

  14. Chlorhexidine Digluconate

    • Günter Kampf
    Pages 429-534

  15. Octenidine Dihydrochloride

    • Günter Kampf
    Pages 535-561

  16. Silver

    • Günter Kampf
    Pages 563-607

  17. Povidone Iodine

    • Günter Kampf
    Pages 609-641

  18. Antiseptic Stewardship for Alcohol-Based Hand Rubs

    • Günter Kampf
    Pages 643-650

  19. Antiseptic Stewardship for Skin Antiseptics

    • Günter Kampf
    Pages 651-660

  20. Antiseptic Stewardship for Surface Disinfectants

    • Günter Kampf
    Pages 661-669
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Keywords

About this book

Various antiseptic agents, such as chlorhexidine, are used for different applications, e.g. in healthcare, veterinary medicine, animal production and household products, including cosmetics. However, not all antiseptic agents provide significant health benefits, especially in some products used in human medicine (alcohol-based hand rubs, antimicrobial soaps).  While some products (antimicrobial soaps, surface disinfectants, instrument disinfectants, wound antiseptics) may contain one or more biocidal agents with a comparable antimicrobial efficacy but large differences in their potential for microbial adaptation and tolerance. An increased bacterial resistance has been described for various antimicrobial agents, sometimes including a cross-resistance to antibiotics.
 
The book is the first comprehensive reference resource on antiseptic agents, including their efficacy, natural and acquired resistance, adaptation, and cross-resistance. It also discusses their and appropriate use in terms of a balance between their efficacy and the risk of acquired bacterial resistance / tolerance. Focusing on human and veterinary medicine and household products, it helps readers make informed decisions concerning against antiseptic products based on their composition. The book contributes to reduce any unnecessary selection pressure towards emerging pathogens and to keep the powerful antiseptic agents for all those applications that have a clear benefit (e.g. reduction of healthcare-associated infection).


Authors and Affiliations

  • Institute of Hygiene and Environmental Medicine, University of Greifswald, Greifswald, Germany

    Günter Kampf

About the author

Günter Kampf is an Associated Professor for Hygiene and Environmental Medicine at the University of Greifswald, Germany. He has published more than 180 mostly international articles on various aspects of infection control, such as hand hygiene and surface disinfection. In 2017 he published his second textbook on hand hygiene in German as an editor. A recognized medical specialist in hygiene and environmental medicine, he worked for a manufacturer of chemical disinfectants for 18 years, the last 5 years of which as Director of Science. Since 2016 he has been self-employed and continues his scientific work together with infection control consultancy for hospitals, medical practices and companies with infection control issues.

Bibliographic Information

  • Book Title: Antiseptic Stewardship

  • Book Subtitle: Biocide Resistance and Clinical Implications

  • Authors: Günter Kampf

  • DOI: https://doi.org/10.1007/978-3-319-98785-9

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2018

  • Hardcover ISBN: 978-3-319-98784-2Published: 05 September 2018

  • Softcover ISBN: 978-3-030-07530-9Published: 11 January 2019

  • eBook ISBN: 978-3-319-98785-9Published: 25 August 2018

  • Edition Number: 1

  • Number of Pages: XLI, 694

  • Number of Illustrations: 3 b/w illustrations, 17 illustrations in colour

  • Topics: Medical Microbiology, Infectious Diseases, Environmental Health

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