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Cerebrospinal Fluid Disorders

Lifelong Implications

  • Book
  • © 2019

Overview

Editors:
  1. David D. Limbrick Jr.

    1. Department of Neurological Surgery, Washington University School of Medicine, St. Louis Children’s Hospital, St. Louis, USA

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  2. Jeffrey R. Leonard

    1. Nationwide Children’s Hospital, Department of Neurosurgery, The Ohio State University College of Medicine, Columbus, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • The first resource available that compiles recent laboratory advances with current clinical treatment.

  • Presents the current treatments for hydrocephalus across the lifespan.

  • Written by experts in the field.

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-xii
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  2. Normal and Abnormal CSF Physiology

    1. Front Matter

      Pages 1-1
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    2. Physiopathology of Foetal Onset Hydrocephalus

      • Esteban M. Rodríguez, Maria Montserrat Guerra, Eduardo Ortega
      Pages 3-30

    3. Iron and Hydrocephalus

      • Thomas Garton, Jennifer M. Strahle
      Pages 31-45

    4. Cerebrospinal Fluid Biomarkers of Hydrocephalus

      • Albert M. Isaacs, David D. Limbrick Jr.
      Pages 47-70

    5. Intracranial Pulsatility, Cerebrospinal Fluid Flow, and Glymphatic Function in Idiopathic Normal Pressure Hydrocephalus

      • Per Kristian Eide, Geir Ringstad
      Pages 71-84

  3. Clinical Disorders of CSF

    1. Front Matter

      Pages 85-85
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    2. Congenital Hydrocephalus

      • Charuta Gavankar Furey, Prince Antwi, Kristopher Thomas Kahle
      Pages 87-113

    3. Genetics of Hydrocephalus: Causal and Contributory Factors

      • Hannah Tully, Annie Laquerriere, Dan Doherty, William Dobyns
      Pages 115-129

    4. Anatomy and Physiology-Based Magnetic Resonance Imaging in Hydrocephalus

      • Smruti K. Patel, Shawn M. Vuong, Weihong Yuan, Francesco T. Mangano
      Pages 131-151

    5. Posthemorrhagic Hydrocephalus

      • Jonathan A. Pindrik, Mark Halverson
      Pages 153-173

    6. Multiloculated Hydrocephalus: Diagnosis, Treatment, and Clinical Implications

      • Eric Anthony Sribnick
      Pages 175-183

    7. Hydrocephalus Secondary to Spina Bifida

      • Michael C. Dewan, John C. Wellons III, Robert P. Naftel
      Pages 185-198

    8. Hydrocephalus and Brain Tumors

      • Jonathan Roth, Shlomi Constantini
      Pages 199-217

    9. Idiopathic Normal Pressure Hydrocephalus

      • Albert M. Isaacs, Mark G. Hamilton, Michael A. Williams
      Pages 219-235

    10. Hydrocephalus Following Aneurysmal Subarachnoid Hemorrhage

      • David L. Dornbos III, Luke G. F. Smith, Varun Shah, Nicholas Musgrave, Patrick P. Youssef, Ciarán J. Powers et al.
      Pages 237-247

    11. Posttraumatic Hydrocephalus

      • Jason Milton, Jeffrey R. Leonard
      Pages 249-258

    12. Management of Intracranial Hypotension and Cerebrospinal Fluid Leaks

      • David L. Dornbos III, Nathaniel Toop, Ammar Shaikhouni, H. Wayne Slone, John M. McGregor
      Pages 259-277

  4. Treatment of CSF Disorders

    1. Front Matter

      Pages 279-279
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    2. Cerebrospinal Fluid Shunting

      • William E. Whitehead
      Pages 281-295
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Keywords

About this book

Hydrocephalus is one of the most common diseases of pediatric and adult neurosurgery. With the introduction of modern neurosurgical procedures, this disease has become a life-long problem.  Even with optimal treatment, there is still significant morbidity and mortality along with a significant cost to the medical system.  This has caused patients and their families to demand improvements in treatments and forced clinicians to evaluate their treatments in large consortiums while utilizing both genetics and technology to improve outcomes or avoid placement of shunt all together.

This text is designed to present the current treatments for hydrocephalus across the lifespan.  The foundation for understanding cerebral spinal fluid (CSF) abnormalities begins with the understanding of physiology and pathogenesis of disease.  These chapters are written by published experts in the field and detail the significant advances in the detection of CSF abnormalities.  This section will discuss the current advances in imaging and current research in biomarkers for both pediatric and adult patients. We will then systematically discuss the treatment of both pediatric and adult CSF disorders.  These will be broken down by cause, since  the physiology of each can be different.  We will end the book with a discussion both of the technological advances and a discussion of consortiums and how they have advanced treatment of this chronic disease.

Reviews

“Cerebrospinal Fluid Disorders: Lifelong Implications allows an important, in-depth insight and knowledge extraction for physicians as well as researchers interested in specific aspects of hydrocephalus research and treatment along with guidance to future research and its potential impact on the health care system.” (Petra M. Klinge, Neurosurgery, Vol. 85 (3), September, 2019)

Editors and Affiliations

  • Department of Neurological Surgery, Washington University School of Medicine, St. Louis Children’s Hospital, St. Louis, USA

    David D. Limbrick Jr.

  • Nationwide Children’s Hospital, Department of Neurosurgery, The Ohio State University College of Medicine, Columbus, USA

    Jeffrey R. Leonard

About the editors

David D. Limbrick, Jr., MD, PhD
Department of Neurological Surgery
Washington University School of Medicine
St. Louis Children’s Hospital
St. Louis, MO
USA



Jeffrey R. Leonard, MD 
Division of Pediatric Neurosurgery
Nationwide Children's Hospital
Department of Neurosurgery
The Ohio State University College of Medicine
Columbus, OH
USA



Bibliographic Information

  • Book Title: Cerebrospinal Fluid Disorders

  • Book Subtitle: Lifelong Implications

  • Editors: David D. Limbrick Jr., Jeffrey R. Leonard

  • DOI: https://doi.org/10.1007/978-3-319-97928-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-319-97927-4Published: 20 November 2018

  • eBook ISBN: 978-3-319-97928-1Published: 10 November 2018

  • Edition Number: 1

  • Number of Pages: XII, 387

  • Number of Illustrations: 38 b/w illustrations, 36 illustrations in colour

  • Topics: Neurosurgery, Primary Care Medicine, Neurology

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