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Drug Delivery for the Retina and Posterior Segment Disease

  • Book
  • © 2018

Overview

Editors:
  1. Jayvadan K. Patel

    1. Faculty of Pharmacy, Sankalchand Patel University, Gujarat, India

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  2. Vijaykumar Sutariya

    1. College of Pharmacy, University of South Florida, Tampa, USA

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  3. Jagat Rakesh Kanwar

    1. School of Medicine, Faculty of Health, Deakin University, Victoria, Australia

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  4. Yashwant V. Pathak

    1. College of Pharmacy, University of South Florida, Tampa, USA

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  • First ever pharmaceutical reference book that consolidates the recent and major literature on the drug delivery for retina and posterior segment diseases

  • Emphasizes the use of implantable devices, iontophoresis as well as micro- and nanoparticles

  • Discusses the challenges and possible improvements to ocular treatment models and sustained release technology

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xix
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  2. Introduction and Basic Concept of Drug Delivery for Retina and Posterior Segment Disease

    1. Front Matter

      Pages 1-1
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    2. Anatomy and Physiology of Retina and Posterior Segment of the Eye

      • Orhan E. Arslan
      Pages 3-33

    3. Pharmacotherapy of Diabetic Macular Edema and Retinopathy

      • Ashley Oake, Charles Preuss, Yashwant V. Pathak
      Pages 35-50

    4. Drug Delivery to Posterior Segment of the Eye: Conventional Delivery Strategies, Their Barriers, and Restrictions

      • Deepak Yadav, Lanke Tejesh Varma, Kiran Yadav
      Pages 51-67

    5. Penetration Routes to Retina and Posterior Segment

      • M. Naveed Yasin, Sachin S. Thakur, Ilva D. Rupenthal
      Pages 69-81

    6. Diabetic Retinopathy: Pathogenesis, Treatment, and Complications

      • Samhitha Gudla, Divya Tenneti, Makrand Pande, Srinivas M. Tipparaju
      Pages 83-94

  3. Nanotechnology Based Formulations for Retina and Posterior Segment Disease

    1. Front Matter

      Pages 95-95
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    2. Liposomes for Retina and Posterior Segment Disease

      • Kathleen Halasz, Yashwant V. Pathak
      Pages 97-106

    3. Nano/Microparticles for Retina and Posterior Diseases

      • Anita Patel, Jayvadan K. Patel, Elie Beit-Yannai
      Pages 107-130

    4. Nonviral Delivery Systems for Gene Therapy for Retina and Posterior Segment Disease

      • Ana del Pozo-Rodríguez, Josune Torrecilla, Alicia Rodríguez-Gascón, María Ángeles Solinís
      Pages 131-149

    5. Oxidative Stress in Ocular Disorders: Exploring the Link to Pesticide Exposure and Potential for Using Nanotechnology for Antioxidant Delivery

      • Pavan Sunkireddy, Bhasker Sriramoju, Kislay Roy, Rupinder Kaur Kanwar, Jagat Rakesh Kanwar
      Pages 151-167

    6. Advances in the Field of Microbial Infection in the Cornea and the Role of Nanotechnology in Treating Keratitis

      • Aseel Al-Mashahedah, Rupinder Kaur Kanwar, Jagat Rakesh Kanwar
      Pages 169-194

    7. Nanomedicine-Based Delivery to the Posterior Segment of the Eye: Brighter Tomorrow

      • Afrah Jalil Abd, Rupinder Kaur Kanwar, Yashwant V. Pathak, Maysaa Al Mohammedawi, Jagat Rakesh Kanwar
      Pages 195-212

  4. Transscleral Iontophoresis for Retina and Posterior Segment Disease

    1. Front Matter

      Pages 213-213
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    2. Transscleral Drug Delivery to Retina and Posterior Segment Disease

      • Ann-Marie Ako-Adounvo, Pradeep K. Karla
      Pages 215-227

    3. Colloidal Carrier Systems for Transscleral Drug Delivery

      • Komal Parmar, Jayvadan K. Patel
      Pages 229-239

    4. Transscleral Iontophoretic Drug Delivery for Treating Retinal Diseases

      • Dherya Bahl, Rinda Devi Bachu, Mrudula Chitti, Pallabita Chowdhury, Jwala Renukuntla, Sai H. S. Boddu
      Pages 241-269

  5. Implant Formulation for Posterior Eye Segment

    1. Front Matter

      Pages 271-271
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    2. Biodegradable Polymeric Implants for Retina and Posterior Segment Disease

      • Aditi Pandhare, Priyanka Bhatt, Hardeep Singh Saluja, Yashwant V. Pathak
      Pages 273-291
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Keywords

About this book

This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.  

Editors and Affiliations

  • Faculty of Pharmacy, Sankalchand Patel University, Gujarat, India

    Jayvadan K. Patel

  • College of Pharmacy, University of South Florida, Tampa, USA

    Vijaykumar Sutariya, Yashwant V. Pathak

  • School of Medicine, Faculty of Health, Deakin University, Victoria, Australia

    Jagat Rakesh Kanwar

About the editors

Dr. Jayvadan K. Patel is a Professor of Pharmaceutics and Principal, Nootan Pharmacy College, Visnagar-384315, Gujarat, India. He has more than 20 years of academic and research experience, has published more than 180 research and review papers in international and national Journals. He is recipients of Very prestigious “APTI Young Pharmacy Teacher Award-2014” by Association of Pharmaceutical Teachers of India. He has completed 12 industry and government sponsored research projects.

Bibliographic Information

  • Book Title: Drug Delivery for the Retina and Posterior Segment Disease

  • Editors: Jayvadan K. Patel, Vijaykumar Sutariya, Jagat Rakesh Kanwar, Yashwant V. Pathak

  • DOI: https://doi.org/10.1007/978-3-319-95807-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2018

  • Hardcover ISBN: 978-3-319-95806-4Published: 20 October 2018

  • Softcover ISBN: 978-3-030-07098-4Published: 25 January 2019

  • eBook ISBN: 978-3-319-95807-1Published: 08 October 2018

  • Edition Number: 1

  • Number of Pages: XIX, 494

  • Number of Illustrations: 21 b/w illustrations, 47 illustrations in colour

  • Topics: Pharmaceutical Sciences/Technology, Ophthalmology

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