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Alagille Syndrome

Pathogenesis and Clinical Management

  • Provides a concise yet comprehensive overview of Alagille syndrome
  • Outlines management challenges, strategies, and future treatment options
  • Written by experts in the field

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eBook USD 69.99
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Softcover Book USD 99.99
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  • Dispatched in 3 to 5 business days
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Hardcover Book USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xiv
  2. Bile Duct Development and the Notch Signaling Pathway

    • Stacey S. Huppert, Kathleen M. Campbell
    Pages 11-31
  3. Genetics of Alagille Syndrome

    • Melissa A. Gilbert, Nancy B. Spinner
    Pages 33-48
  4. Liver Disease in Alagille Syndrome

    • Alyssa Kriegermeier, Andrew Wehrman, Binita M. Kamath, Kathleen M. Loomes
    Pages 49-65
  5. Transplant Considerations in Alagille Syndrome

    • Evelyn Hsu, Elizabeth Rand
    Pages 67-76
  6. Cardiac, Aortic, and Pulmonary Vascular Involvement in Alagille Syndrome

    • Justin T. Tretter, Doff B. McElhinney
    Pages 77-90
  7. Vascular Manifestations in Alagille Syndrome

    • Shannon M. Vandriel, Rebecca N. Ichord, Binita M. Kamath
    Pages 91-102
  8. Skeletal Involvement in Alagille Syndrome

    • Yadav Wagley, Troy Mitchell, Jason Ashley, Kathleen M. Loomes, Kurt Hankenson
    Pages 121-135
  9. Health-Related Quality of Life and Neurocognition in Alagille Syndrome

    • Saeed Mohammad, Estella M. Alonso
    Pages 159-165
  10. Future Therapeutic Approaches for Alagille Syndrome

    • Emma R. Andersson
    Pages 167-193
  11. Back Matter

    Pages 195-198

About this book

This text provides a concise yet comprehensive overview of Alagille syndrome. The book reviews the pathophysiology and genetics of the disorder, discusses recent molecular advances and its impact on diagnostics, and describes management challenges and strategies. The text also touches upon future treatment options.


Written by experts in the field, Alagille Syndrome: Pathogenesis and Clinical Management is a valuable resource for physicians and researchers dealing with this disorder, one that will help guide patient management and stimulate investigative efforts.  

Editors and Affiliations

  • Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Canada

    Binita M. Kamath

  • Division of Gastroenterology, Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia, USA

    Kathleen M. Loomes

About the editors

Binita M. Kamath, MBBChir MRCP MTR
The Hospital for Sick Children
Division of Gastroenterology, Hepatology and Nutrition 
Toronto, ON
Canada


Kathleen M. Loomes, MD
Children’s Hospital of Philadelphia
Division of Gastroenterology, Hepatology and Nutrition
Department of Pediatrics
Philadelphia, PA
USA

 

Bibliographic Information

  • Book Title: Alagille Syndrome

  • Book Subtitle: Pathogenesis and Clinical Management

  • Editors: Binita M. Kamath, Kathleen M. Loomes

  • DOI: https://doi.org/10.1007/978-3-319-94571-2

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2018

  • Hardcover ISBN: 978-3-319-94570-5Published: 09 October 2018

  • Softcover ISBN: 978-3-030-06878-3Published: 08 January 2019

  • eBook ISBN: 978-3-319-94571-2Published: 26 September 2018

  • Edition Number: 1

  • Number of Pages: XIV, 198

  • Number of Illustrations: 10 b/w illustrations, 31 illustrations in colour

  • Topics: Gastroenterology, Hepatology, Cardiology

Buy it now

Buying options

eBook USD 69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access