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Diabetic Nephropathy

Pathophysiology and Clinical Aspects

  • Covers all the current knowledge regarding diabetic nephropathy

  • Presented in an integrated “bench-to-bedside” approach

  • Written by international experts in the field

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Table of contents (29 chapters)

  1. Front Matter

    Pages i-xvi
  2. Diabetic Nephropathy: Scope of the Problem

    1. Front Matter

      Pages 1-1
    2. Clinical Features and Natural Course of Diabetic Nephropathy

      • Peter Rossing, Marie Frimodt-Møller
      Pages 21-32
    3. Global, Regional, and Ethnic Differences in Diabetic Nephropathy

      • Oluwatoyin I. Ameh, Ikechi G. Okpechi, Charles Agyemang, Andre P. Kengne
      Pages 33-44
    4. Renal Disease in Obesity, Metabolic Syndrome and Diabesity

      • Esteban Porrini, Maruja Navarro-Díaz, Rosa Rodríguez-Rodríguez, Eduardo Salido
      Pages 65-80
  3. Pathophysiology and Clinical Pathology of the Diabetic Kidney

    1. Front Matter

      Pages 81-81
    2. Introduction to Pathogenetic Mechanisms of Diabetic Nephropathy

      • Liffert Vogt, Joris J. Roelofs
      Pages 83-87
    3. The Genetics of Diabetic Nephropathy

      • Marcus G. Pezzolesi, Andrzej S. Krolewski
      Pages 89-112
    4. Pathology of the Kidney in Diabetes

      • Behzad Najafian, Charles E. Alpers
      Pages 113-140
  4. The Glomerulus

    1. Front Matter

      Pages 141-141
    2. The Mesangial Cell in Diabetic Nephropathy

      • Tri Q. Nguyen, Roel Goldschmeding
      Pages 143-151
    3. The Glomerular Endothelium in Diabetic Nephropathy: Role of Heparanase

      • Johan van der Vlag, Baranca Buijsers
      Pages 153-170
    4. The Podocyte in Diabetic Nephropathy: Recent Advances

      • Gavin I. Welsh, Richard J. Coward
      Pages 171-182
    5. Inflammatory Processes in Diabetic Glomeruli

      • Daphne H. T. IJpelaar
      Pages 183-194
  5. The Tubulointerstitium

    1. Front Matter

      Pages 195-195
    2. Proteinuria and Tubulotoxicity

      • Norberto Perico, Ariela Benigni, Giuseppe Remuzzi
      Pages 197-214
    3. Tubuloglomerular Communication in Diabetic Nephropathy

      • Shu Wakino, Kazuhiro Hasegawa, Hiroshi Itoh
      Pages 215-226
    4. Mechanisms of Interstitial Fibrosis in Diabetic Nephropathy

      • Ivonne Loeffler, Gunter Wolf
      Pages 227-251

About this book

This book provides an overview of the most up-to-date research on diabetic nephropathy and the current understanding of its pathogenesis, clinical features and socio-economic developments. Written by leading experts in the field, it provides a comprehensive synthesis of clinical and pathophysiological aspects from a mechanism-based point of view, and reviews evidence-based treatment modalities for the prevention and management of diabetic nephropathy. In addition, closely related areas such as diabesity, diabetic eye disease and macrovascular involvement in diabetes are addressed.

Diabetic Nephropathy will be of interest for nephrologists, diabetologists, internists, transplant physicians, public health professionals, basic scientists, geneticists, epidemiologists, pathologists, and molecular and cell biologists working in the field of diabetes and its complications.


Reviews

“This book will be suitable for basic researchers, practicing nephrologists/diabetologists/internists, fellows, residents, medical students, and public health workers. … this is an excellent source of answers to a great many questions that arise while dealing with diabetes and its numerous effects. It fills a big gap and comes to the rescue at a time of need.” (Amita Maibam, Doody's Book Reviews, May 31, 2019)

Editors and Affiliations

  • Department of Pathology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands

    Joris J. Roelofs

  • Department of Internal Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands

    Liffert Vogt

About the editors

Joris J. Roelofs, MD, PhD

Joris Roelofs (1972) studied medicine at the KU Leuven, Belgium, and the VUmc School of Medical Sciences, Amsterdam, the Netherlands, where he received his MD degree. He received his PhD degree from the University of Amsterdam Faculty of Medicine with studies on coagulation in renal disease, after which he worked as a Postdoctoral Research Fellow in the Kirkland Center for Lupus Research (Cornell University Medical College, New York City). Joris Roelofs is Associate Professor of Renal Pathology and Principal Investigator in the Department of Pathology at the Academic Medical Center, Amsterdam, where he leads translational studies in chronic kidney disease and diabetic nephropathy.

Liffert Vogt, MD, PhD

Liffert Vogt (1975) was born in Groningen in the Netherlands, where he completed his medical degree and nephrology PhD. He then moved to the Mario Negri Institute, Bergamo, Italy where he was an international postdoctoral fellow, and then he completed his internal medicine and nephrology training at the Academic Medical Center, Amsterdam, the Netherlands, where he works now as an internist and nephrologist. As a Principal Investigator in his institute, he is leading experimental and clinical studies within the field of diabetes and chronic kidney disease.

Bibliographic Information

  • Book Title: Diabetic Nephropathy

  • Book Subtitle: Pathophysiology and Clinical Aspects

  • Editors: Joris J. Roelofs, Liffert Vogt

  • DOI: https://doi.org/10.1007/978-3-319-93521-8

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2019

  • Hardcover ISBN: 978-3-319-93520-1Published: 08 November 2018

  • Softcover ISBN: 978-3-030-06678-9Published: 08 January 2019

  • eBook ISBN: 978-3-319-93521-8Published: 29 October 2018

  • Edition Number: 1

  • Number of Pages: XVI, 548

  • Number of Illustrations: 14 b/w illustrations, 67 illustrations in colour

  • Topics: Diabetes, Pathology

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access