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  • © 2019

Cardiovascular Complications in Cancer Therapy

  • Provides a comprehensive yet concise resource.
  • Provides a guide for the clinician facing cardiovascular toxicity in cancer and hematologic patients.
  • Written by experts in the field.

Part of the book series: Current Clinical Pathology (CCPATH)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xiii
  2. Introduction

    • Antonio Russo, Giuseppina Novo, Patrizio Lancellotti, Fausto J. Pinto, Antonio Giordano
    Pages 1-2
  3. Mechanisms of Cardiovascular Damage Induced by Traditional Chemotherapy

    • Valentina Mercurio, Giulio Agnetti, Pasquale Pagliaro, Carlo G. Tocchetti
    Pages 3-14
  4. Molecular Mechanisms of Cardiovascular Damage Induced by Anti-HER-2 Therapies

    • Valentina Mercurio, Giulio Agnetti, Pasquale Pagliaro, Carlo G. Tocchetti
    Pages 15-19
  5. Cardiovascular Damage Induced by Radiotherapy

    • Antonio Galvano, Giuseppina Novo, Mario Roselli, Antonio Giordano, Antonio Russo
    Pages 21-31
  6. Cardiovascular Damage Induced by Anti-VEGF Therapy

    • Giuseppina Novo, Daniela Di Lisi, Enrico Bronte, Manuela Fiuza, Fausto J. Pinto
    Pages 33-44
  7. Cardiovascular Damage Induced by Anti-BCR-ABL TKIs

    • Giuseppina Novo, Daniela Di Lisi, Manuela Fiuza, Fausto J. Pinto
    Pages 45-55
  8. Heart Failure and Left Ventricular Dysfunction

    • Giuseppina Novo, Cinzia Nugara, Patrizio Lancellotti
    Pages 57-69
  9. Coronary Artery Disease

    • Giuseppe Mercuro, Christian Cadeddu Dessalvi, Martino Deidda, Stephan Stöbe, Andreas Hagendorff
    Pages 71-82
  10. Peripheral Artery Disease and Stroke

    • Concetta Zito, Roberta Manganaro, Scipione Carerj, Fausto J. Pinto, Bijoy J. Kandheria
    Pages 83-92
  11. Valvular Heart Disease

    • Ines Paola Monte, Gyanendra Kumar Sharma
    Pages 93-98
  12. Arterial Hypertension

    • Paolo Spallarossa, Giacomo Tini, Daniel Lenihan
    Pages 99-111
  13. Atrial Fibrillation in Cancer

    • Dimitrios Farmakis, George Papingiotis, Gerasimos Filippatos, Annamaria Bonelli, Nicola Maurea
    Pages 113-121
  14. Management of QT Prolongation Induced by Anticancer Drugs

    • Nicola Maurea, Rolando Paciello, Carmela Coppola, Dimitrios Farmakis
    Pages 123-132
  15. Pulmonary Hypertension Induced by Anticancer Drugs

    • Valentina Mercurio, Giulio Agnetti, Pasquale Pagliaro, Carlo G. Tocchetti
    Pages 133-139
  16. Venous Thromboembolism

    • Nicola Maurea, Antonietta Caronna, Elie N. Mouhayar
    Pages 141-150
  17. Early Detection of Cardiac Damage

    • Giuseppina Novo, Cinzia Nugara, Patrizio Lancellotti
    Pages 151-163
  18. Diagnosis of Cardiac Damage: Role of Stress Echo

    • Ciro Santoro, Roberta Esposito, Covadonga Fernández-Golfín, Maurizio Galderisi, Jose Luis Zamorano Gomez
    Pages 165-172
  19. Early Detection and Monitoring of Vascular Damage

    • Ciro Santoro, Roberta Esposito, Covadonga Fernández-Golfín, Jose Luis Zamorano Gomez, Maurizio Galderisi
    Pages 173-182

About this book

This proposed text is designed to provide a useful and comprehensive resource and state-of-the-art overview to readers about vascular damage  potentially induced by antineoplastic drugs. 
Thanks to more and more effective antineoplastic treatments the survival of cancer patients is enormously increasing, but at the same time it is increasing the burden of related cardiovascular complications that affect morbidity and mortality. On this basis a new branch of cardiology has been developed, that is Cardio-Oncology. The aim is to prevent cardiovascular complications related to cancer therapy and to facilitate and avoid interruption of antineoplastic drugs due to the occurrence of cardiovascular damage. An increasing attention has been given to cardiac damage, while, until today, vascular complications have been poorly evaluated. 
The aim of this book is to focus on vascular complications related to cancer treatment, to guide the clinician at facing,during his every day practice, cardiovascular toxicity in cancer and hematologic patients. 
The proposed sections of the book have been structured to review the molecular mechanisms underlying vascular damage induced by new and old treatments, to describe the various manifestations of vascular disease that may range from artery to venous disease (including coronary artery disease, peripheral arterial disease, venous thromboembolism and pulmonary hypertension), and to provide advice to monitor patients undergoing onco-hematologic treatments in order to prevent and eventually manage vascular damage.
This book will address resident and fellow physicians, medical oncologists, cardiologists, general practitioners and all those who take care of these patients.
All invited authors will be recognized experts in their field, and leading international researchers on these topics. The editor has worked with these expert colleagues on a variety of other projects.The authors will provide their manuscript according to current literature and clinical research studies. 
The book does not seek to duplicate or replace other current resources. Rather, it will create a comprehensive yet concise resource on this emerging topic that is not adequately covered by any current literature.


Editors and Affiliations

  • Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, Palermo, Italy

    Antonio Russo

  • University of Palermo, School of Medicine, Palermo, Italy

    Giuseppina Novo

  • Department of Cardiology, University of Liège, Liege, Belgium

    Patrizio Lancellotti

  • Temple University College of Science and Technology, Philadelphia, USA

    Antonio Giordano

  • Cardiology Department, University of Lisbon, Lisbon, Portugal

    Fausto J. Pinto

About the editors

Antonio Russo, MD, PhD
Full Professor of Medical Oncology
Department of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.)
University of Palermo, Italy
Director of Medical Oncology Section, University Hospital P. Giaccone
Palermo, Italy 


Giuseppina Novo, MD, PhD
Associate Professor of Cardiology
Biomedic Department of Internal Medicine and Specialities (DIBIMIS) University of Palermo, Italy
Division of Cardiology, University Hospital P. Giaccone
Palermo, Italy


Patrizio Lancellotti, MD, PhD
University of Liège Hospital, GIGA Cardiovascular Sciences
Department of Cardiology
CHU Sart Tilman, Liège, Belgium
Gruppo Villa Maria Care and Research, Anthea Hospital
Bari, Italy


Antonio Giordano, MD PhD 
Director, Sbarro Institute for Cancer Research and Molecular Medicine and Center of Biotechnology
College of Science and Technology
Temple University
PA 19122
USA


Fausto J. Pinto, MD, PhD, FESC, FACC, FSCAI, FASE
Professor, University Hospital Santa Maria, CHLN
University of Lisbon, Portugal
Dept. of Cardiology
Av Prof Egas Moniz
Lisboa 1649-028 Portugal




Bibliographic Information

  • Book Title: Cardiovascular Complications in Cancer Therapy

  • Editors: Antonio Russo, Giuseppina Novo, Patrizio Lancellotti, Antonio Giordano, Fausto J. Pinto

  • Series Title: Current Clinical Pathology

  • DOI: https://doi.org/10.1007/978-3-319-93402-0

  • Publisher: Humana Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-319-93401-3Published: 18 October 2018

  • Softcover ISBN: 978-3-030-06653-6Published: 01 February 2019

  • eBook ISBN: 978-3-319-93402-0Published: 04 October 2018

  • Series ISSN: 2197-781X

  • Series E-ISSN: 2197-7828

  • Edition Number: 1

  • Number of Pages: XIII, 224

  • Number of Illustrations: 3 b/w illustrations, 38 illustrations in colour

  • Topics: Oncology, Cardiology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access