Drug-Coated Balloons

1. Front Matter

   Pages i-viii

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2. From Drug-Eluting Balloon to Drug-Coated Balloon … to Eradication of Intracoronary Metal, a New Ending Story

   • Patrick W. Serruys, Kuniaki Takahashi

   Pages 1-7

3. History of Drug-Coated Balloons

   • Dario Buccheri, Bernardo Cortese

   Pages 9-13

4. Previous Mistakes with DCB Technology, and How to Prevent Them in the Future

   • Dario Buccheri, Bernardo Cortese

   Pages 15-19

5. Local Drug Delivery to Prevent Restenosis of the Coronary and Peripheral Arteries

   • Carlo Zivelonghi, Pierfrancesco Agostoni, Freek Nijhoff

   Pages 21-34

6. Technical Insights on Drug-Coated Balloons

   • Marco Ferrone, Juan F. Granada

   Pages 35-43

7. Technical Insights on Drug-Coated Balloons II

   • Manish Doshi, Prakash Sojitra, Dinesh Shah, Sameer Dani, Alexandre Abizaid

   Pages 45-57

8. Design Parameters for Drug-Coated Balloons II

   • Manish Doshi, Dinesh Shah, Prakash Sojitra

   Pages 59-67

9. Potential Clinical Advantages of Drug-Coated Balloon in Specific Clinical Settings

   • Serdar Farhan, Birgit Vogel, Roxana Mehran

   Pages 69-79

10. The Use of Drug-Coated Balloons for Patients with In-Stent Restenosis

    • Fernando Alfonso, Javier Cuesta, Fernando Rivero, Marcos García Guimaraes, Teresa Bastante, Bernardo Cortese

    Pages 81-92

11. Drug-Coated Balloons in Native Coronary Artery Disease

    • Mostafa Elwany, Bernardo Cortese

    Pages 93-109

12. Drug-Eluting Balloons in Coronary Bifurcation Lesions

    • Anouar Belkacemi, Pieter R. Stella

    Pages 111-119

13. Dissection Management with Drug-Coated Balloons

    • Gaetano Di Palma, Bernardo Cortese

    Pages 121-128

14. The Role of Drug-Coated Balloons on Late Lumen Enlargement

    • U. Wickramarachchi, S. C. Eccleshall

    Pages 129-138

15. Sirolimus-Coated Balloon: Insights on a New Technology for Coronary Use

    • Gaetano Di Palma, Bernardo Cortese

    Pages 139-149

16. Drug-Coated Balloon in Superficial Femoral Artery In-Stent Restenosis

    • Donato Gerardi, Arturo Alfani, Giovanni Esposito, Eugenio Stabile

    Pages 151-158

17. Drug-Coated Balloons for Native Femoro-popliteal Disease

    • Dario Pellegrini, Bernardo Cortese

    Pages 159-180

18. The Role of Drug-Coated Balloon for the Treatment of Native Below-the-Knee Arteries

    • Roberto Nerla, Fausto Castriota, Alberto Cremonesi, Antonio Micari

    Pages 181-188

19. Drug-Coated Balloons: Lessons from the Real World

    • Damiano Regazzoli, Marco Bruno Ancona, Pier Pasquale Leone, Azeem Latib

    Pages 189-201

20. Stent Use After Drug-Coated Balloons

    • Satoru Mitomo, Richard J. Jabbour, Damiano Regazzoli, Azeem Latib, Antonio Colombo

    Pages 203-208

This book provides a comprehensive, up-to-date summary of drug-coated balloon (DCB) technology and the role of DCBs in the treatment of coronary and peripheral arterial disease. In addition to clear explanation of how DCBs works, readers will find an enlightening analysis of the mistakes and successes of the past decade and the emergence of the latest delivery systems, which combine a more deliverable device with much improved drug delivery to the vessel wall. The full range of current applications of DCBs are reviewed in detail, drawing on the latest scientific evidence. Due attention is paid to newer devices, with provision of technical insights and documentation of the available clinical data. Ongoing research projects, remaining technical challenges, likely future directions, and reimbursement issues are also carefully considered. This book will be a useful tool for any interventional cardiologist, interventional radiologist, or vascular surgeon who wishes to acquire a deep knowledge of this technology and its application in both coronary and peripheral interventions.

• drug-eluting balloon
• angioplasty without scaffold
• angioplasty without metal
• in-stent restenosis
• vessel dissection healing
• lumen gain
• late lumen enlargement
• pharmacotherapy

• Cardiac Department, San Carlo Clinic, Milano, Italy

  Bernardo Cortese

Dr Cortese is Interventional Cardiologist and Chief of Research, Innovation and Development of the Cardiac Dpt at Fatebenefratelli Hospital in Milan, Italy. His main contests of interest are new technologies in the catheterization laboratory, including drug-coated balloons and bioresorbable scaffolds. Dr Cortese is one of the most world-renowned experts  in drug-coated balloons technology, and among other contributions he conceived and published the Italian Guidelines on Drug-Eluting Balloon angioplasty in the coronary field, that were endorsed by the Italian Scientific Society of Interventional Cardiology (GISE); the International Guidelines on Drug-Eluting Balloon angioplasty in the peripheral field, published in the European Heart Journal in 2016. Since 2014 Dr Cortese  is member of the Scientific Committee of the Italian Society of Interventional Cardiology. He is involved in several educational programs, including the “DEB School”, and he is author of more than 120 publications indexed in Pubmed.

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