Skip to main content
  • Book
  • © 2018

Cerebral Ischemic Reperfusion Injuries (CIRI)

Bench Research and Clinical Implications

  • Thorough review of the mechanisms behind cerebral ischemic reperfusion injuries
  • Brings together important pre-clinical research with a eye to informing future therapeutic interventions
  • Topics addressed include recanalization, no or low reflow, blood pressure, collateral circulation, inflammation and immunity, oxidative stress, and brain edema

Part of the book series: Springer Series in Translational Stroke Research (SSTSR)

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (16 chapters)

  1. Front Matter

    Pages i-xvii
  2. Gelatinase-Mediated Impairment of Microvascular Beds in Cerebral Ischemia and Reperfusion Injury

    • Shanyan Chen, Hailong Song, Jiankun Cui, Joel I. Shenker, Yujie Chen, Grace Y. Sun et al.
    Pages 1-14
  3. Characters of Ischemic Stroke and Recanalization Arteries

    • Qingqing Dai, Shujuan Li, Junfa Li
    Pages 15-34
  4. Cerebral Ischemic Reperfusion Injury (CIRI) Cases

    • Weijian Jiang, Yi-Qun Zhang
    Pages 35-41
  5. CIRI After Early Recanalization

    • Qingmeng Chen, Min Lou
    Pages 43-56
  6. Programmed Cell Death in CIRI

    • Ruili Wei, Yang Xu, Jie Zhang, Benyan Luo
    Pages 57-82
  7. Reactive Astrocytes in Cerebral Ischemic Reperfusion Injury

    • Abhishek Mishra, Rachana Nayak, Dandan Sun
    Pages 83-100
  8. Oxidative Stress and Nitric Oxide in Cerebral Ischemic Reperfusion Injury

    • Junning Ma, Zhong Liu, Zhongsong Shi
    Pages 101-119
  9. Extracellular Matrix in Stroke

    • Yao Yao
    Pages 121-144
  10. Inflammation and Ischemic Stroke

    • Junwei Hao, Kai Zheng, Heng Zhao
    Pages 145-161
  11. Ischemia/Reperfusion Damage in Diabetic Stroke

    • Poornima Venkat, Michael Chopp, Jieli Chen
    Pages 171-192
  12. Blood Pressure and Cerebral Ischemic Reperfusion Injury

    • Weijian Jiang, Chen Li, Mohamad Orabi, Wuwei Feng
    Pages 205-213
  13. Collateral Circulation and Cerebral Reperfusion After Ischemic Stroke

    • Qinghai Huang, Wanling Wen, Myles McCrary, Ling Wei
    Pages 215-230
  14. Controlled Reperfusion Against Ischemia Reperfusion Injury

    • Weijian Jiang, Jin Lv, Ying-Ying Zhang, Kai Wang
    Pages 231-243

About this book

This volume is focused on subjects related to cerebral ischemia and reperfusion injuries after acute stroke. All chapters are selected from the Sixth Elite Stroke meeting named Pangu Stroke Conference and written by members of world leading laboratories of stroke studies. The contents cover both clinical and bench studies, from basic components of cerebral arterial system to clinical reperfusion injury cases, from reperfusion caused programmed cell death and astrocyte activation to oxidative stress and nitric oxide after reperfusion, from extracellular matrix and inflammation to a role of diabetes after reperfusion, from small artery disorders to collateral circulation and blood pressure control after reperfusion.

Wei-Jian Jiang, Chairman of New Era Stroke Care and Research Institute of PLA Rocket Force General Hospital, Beijing, China.

Wengui Yu, Professor and Director of Comprehensive Stroke & Cerebrovascular Center, University of California, Irvine

YanQu, Professor and Director of Neurosurgery at the Second Affiliated Hospital of Air Force Medical University, Xi’an, China.

Zhongsong Shi, Professor of Neurosurgery at Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Ben-yan Luo, Professor and Chair of Neurology at the First Affiliated Hospital of Zhejiang University.

John H. Zhang, Professor of Anesthesiology and Physiology at Loma Linda University School of Medicine, Loma Linda, CA, USA.

Editors and Affiliations

  • Department of Vascular Neurosurgery, PLA Rocket Force General Hospital, Beijing, China

    Weijian Jiang

  • Department of Neurology, University of California Irvine, Irvine, USA

    Wengui Yu

  • Department of Neurosurgery, Tangdu Hospital of Air Force Medical University, Xi’an, China

    Yan Qu

  • Department of Neurosurgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China

    Zhongsong Shi

  • Department of Neurology, The First Affiliated Hospital School of Medicine, Zhejiang University, Hangzhou, China

    Benyan Luo

  • Department of Anesthesiology, Loma Linda University, Loma Linda, USA

    John H. Zhang

Bibliographic Information

  • Book Title: Cerebral Ischemic Reperfusion Injuries (CIRI)

  • Book Subtitle: Bench Research and Clinical Implications

  • Editors: Weijian Jiang, Wengui Yu, Yan Qu, Zhongsong Shi, Benyan Luo, John H. Zhang

  • Series Title: Springer Series in Translational Stroke Research

  • DOI: https://doi.org/10.1007/978-3-319-90194-7

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2018

  • Hardcover ISBN: 978-3-319-90193-0Published: 14 July 2018

  • Softcover ISBN: 978-3-030-07958-1Published: 21 December 2018

  • eBook ISBN: 978-3-319-90194-7Published: 29 June 2018

  • Series ISSN: 2363-958X

  • Series E-ISSN: 2363-9598

  • Edition Number: 1

  • Number of Pages: XVII, 259

  • Number of Illustrations: 11 b/w illustrations, 29 illustrations in colour

  • Topics: Neurosciences, Neurology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access