Prospects of Plant-Based Vaccines in Veterinary Medicine

1. Front Matter

   Pages i-viii

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2. History and Promise of Plant-Made Vaccines for Animals

   • Ed Rybicki

   Pages 1-22

3. Plant Transformation Strategies

   • Verónica Araceli Márquez-Escobar, Omar González-Ortega, Sergio Rosales-Mendoza

   Pages 23-42

4. Vaccines for Wild, Feral and Companion Animals

   1. Front Matter

      Pages 43-43

      PDF

   2. Rabies and Related Lyssaviruses

      • Charles E. Rupprecht, Rachel Chikwamba

      Pages 45-87

   3. A Comprehensive Review of Toxoplasma Gondii Biology and Host-Cell Interaction: Challenges for a Plant-Based Vaccine

      • Valeria Sander, Sergio O. Angel, Marina Clemente

      Pages 89-120

   4. Vaccines Against West Nile Virus

      • Haiyan Sun, Qiang Chen

      Pages 121-146

5. Vaccines for Poultry

   1. Front Matter

      Pages 147-147

      PDF

   2. Plant-Made Veterinary Vaccines for Newcastle Disease Virus

      • David R. Thomas, Amanda M. Walmsley

      Pages 149-167

   3. Infectious Bursal Disease Virus

      • Evangelina Gómez, María Soledad Lucero, Matías Richetta, Silvina Chimeno Zoth, Analía Berinstein

      Pages 169-187

   4. Plant-Produced Avian Influenza Antigens

      • Yanaysi Ceballo, Alina Lopez, Kenia Tiel, Abel Hernandez

      Pages 189-208

   5. Plant-Made Vaccines Against Avian Reovirus

      • Ching-Chun Chang, Hung-Jen Liu

      Pages 209-223

6. Vaccines for Swine

   1. Front Matter

      Pages 225-225

      PDF

   2. Toward the Optimization of a Plant-Based Oral Vaccine Against Cysticercosis

      • Edda Sciutto, Marisela Hernández, Jacquelynne Cervantes-Torres, Elizabeth Monreal-Escalante, Omayra Bolaños-Martínez, Juan Francisco Rodríguez et al.

      Pages 227-237

   3. Classical Swine Fever Virus

      • Han Sang Yoo

      Pages 239-254

   4. Porcine Epidemic Diarrhea Virus

      • Zayn Khamis, Rima Menassa

      Pages 255-266

   5. Porcine Reproductive and Respiratory Syndrome (PRRS)

      • Elizabeth Loza-Rubio, Edith Rojas-Anaya

      Pages 267-281

7. Vaccines for Ruminants

   1. Front Matter

      Pages 283-283

      PDF

   2. The Benefit of a Plant-Based Cattle Vaccine for Reducing Enterohemorrhagic Escherichia Coli Shedding and Improving Food Safety

      • Adam Chin-Fatt, Ed Topp, Rima Menassa

      Pages 285-310

   3. Foot-and-mouth Disease

      • Vanesa Ruiz, Andrés Wigdorovitz

      Pages 311-343

This book provides an in-depth explanation of the advantages and current limitations of recombinant plant-made vaccines for use in veterinary medicine, including for livestock, pets, and wild animals. Written by top scientists in the field, it discusses the background to and latest scientific advances in plant-made vaccines for the most commonly targeted veterinary infections. 


With the recent high-profile research into recombinant plant-made therapeutics for Ebola and Zika viruses, it is likely that the products will be commercialized and widely used in the future. Plant-made therapeutics have a variety of advantages over those made in traditional systems; however, their most fruitful application may be in veterinary medicine, due to less stringent regulations and a greater need for low-cost products.

• Molecular farming
• Plant biotechnology
• Veterinary vaccine
• Animal health
• Recombinant plant-made vaccines
• Livestock
• Plant-made therapeutics
• Aquaculture
• Pets
• Rabies
• Avian influenza
• vaccines

• Western University, London, Canada

  Jacqueline MacDonald

Jacqueline MacDonald earned a PhD in the Department of Chemical Engineering at the University of Toronto. With a strong background in molecular biology, she has worked with plants, animals, fungi, and bacteria, mostly with biotechnological applications. Her postdoctoral work involved plant-produced vaccine candidates for livestock with the goal of reducing the environmental and public health effects of antibiotics. Jacqueline currently teaches biotechnology, environmental sustainability, and health sciences at both Western University and Fanshawe College in London, Ontario, Canada.

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