Editors:
- A field-defining volume containing both the background and latest advances in the science of the Exposome
- Provides a state of the art on techniques and methodologies for measuring the human Exposome as well as an overview on statistical and computational techniques for characterizing the Exposome
- Features chapters written by a “Who’s who” in this young but rapidly-growing field
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Table of contents (17 chapters)
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Front Matter
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The Utility of the Exposome Paradigm
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Front Matter
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Measuring the Internal Exposome
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Front Matter
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Measuring Sources of Exposure
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Front Matter
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Exposome Characterization Around the Globe
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Front Matter
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About this book
The term “Exposome” describes the sum of all exposures (not only chemical) that an individual can receive over a lifetime from both exogenous sources (environmental contaminants, food, lifestyle, drugs, air, etc.) and endogenous sources (metabolism, oxidative stress, lipid peroxidation, chemicals synthesized by the microbiome, etc.). The first section of this book contains chapters that discuss how the Exposome is defined and how the concept fits into the fields of public health and epidemiology. The second section provides an overview of techniques and methods to measure the human Exposome. The third section contains methods and applications for measuring the Exposome through external exposures. Section four provides an overview on statistical and computational techniques- including big data analysis - for characterizing the Exposome. Section five presents a global collection of case studies
Editors and Affiliations
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Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK
Sonia Dagnino
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The Johns Hopkins School of Medicine, Agilent Technologies, Baltimore, USA
Anthony Macherone
About the editors
Dr. Sonia Dagnino is currently a Marie Sklodowska-Curie Research Fellow at the Epidemiology and Biostatistics Department at Imperial College London, School of Public Health. Dr. Sonia Dagnino's research is focused on the development of new methodologies for the understanding of the exposome and its implications for human health. Dr. Dagnino is actively engaged in several research projects on the exposome worldwide and has an extensive expertise in this field.
Dr. Macherone serves as a Senior Scientist with Agilent Technologies and a Visiting Professor at the Johns Hopkins School of Medicine. He is also on the faculty of P2i (Preconception 2 infancy) with a focus of providing “women and couples tools to improve their odds of healthy, full-term pregnancies, thus reducing the incidence of serious, chronic disorders among their children”. Dr. Macherone is an expert in exposomics and is actively engaged in several publicly or privately funded exposomics investigations.Bibliographic Information
Book Title: Unraveling the Exposome
Book Subtitle: A Practical View
Editors: Sonia Dagnino, Anthony Macherone
DOI: https://doi.org/10.1007/978-3-319-89321-1
Publisher: Springer Cham
eBook Packages: Earth and Environmental Science, Earth and Environmental Science (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2019
Hardcover ISBN: 978-3-319-89320-4Published: 20 October 2018
Softcover ISBN: 978-3-030-07739-6Published: 29 December 2018
eBook ISBN: 978-3-319-89321-1Published: 08 October 2018
Edition Number: 1
Number of Pages: XII, 447
Number of Illustrations: 13 b/w illustrations, 47 illustrations in colour
Topics: Environmental Health, Ecotoxicology, Public Health, Epidemiology, Human Genetics, Bioinformatics