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Synthetic Cathinones

Novel Addictive and Stimulatory Psychoactive Substances

  • First book to explore the chemical structure, detection, and usage of synthetic cathinones
  • Intended for scientists, clinicians, and academicians
  • Discusses acute and chronic toxicity of synthetic cathinones

Part of the book series: Current Topics in Neurotoxicity (Current Topics Neurotoxicity, volume 12)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
  2. Synthetic Cathinones: Neurotoxic Health Hazards and Potential for Abuse

    • Trevor Archer, Richard M. Kostrzewa
    Pages 1-10
  3. Novel Psychoactive Substances: Classification and General Information

    • Jolanta B. Zawilska, Jakub Wojcieszak
    Pages 11-24
  4. Khat—A Natural Source of Cathinone

    • Nilesh B. Patel
    Pages 25-40
  5. Metabolism of Synthetic Cathinones

    • Kei Zaitsu
    Pages 71-96
  6. Effects of Synthetic Cathinones on Brain Neurotransmitters

    • Krystyna Gołembiowska, Katarzyna Kamińska
    Pages 117-124
  7. Behavioral Profiles and Underlying Transmitters/Circuits of Cathinone-Derived Psychostimulant Drugs of Abuse

    • Steven J. Simmons, Erin Kim, Taylor A. Gentile, Ali Murad, John W. Muschamp, Scott M. Rawls
    Pages 125-152
  8. Synthetic Cathinones—Prevalence and Motivations for Use

    • John M. Corkery, Amira Guirguis, Duccio G. Papanti, Laura Orsolini, Fabrizio Schifano
    Pages 153-189
  9. The Effects and Risks Associated with Synthetic Cathinones Use in Humans

    • Laurent Karila, Amine Benyamina
    Pages 191-202
  10. Back Matter

    Pages 205-207

About this book

Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called β-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years.

Synthetic cathinones – novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.

Editors and Affiliations

  • Department of Pharmacodynamics, Medical University of Łódź, Łódź, Poland

    Jolanta B. Zawilska

About the editor

Jolanta Zawilska is Professor at the Academy of Sciences in Lodz, Poland and Chief of the Chronobiology lab at the Centre for Medical Biology. Dr. Zawilska obtained her PhD in Pharmacology  at the Medical University of Lodz. She has over 35 years of experience in pharmacology/pharmacodynamics and chronobiology. She has written numerous publications and has received awards in recognition of her research.

Bibliographic Information

  • Book Title: Synthetic Cathinones

  • Book Subtitle: Novel Addictive and Stimulatory Psychoactive Substances

  • Editors: Jolanta B. Zawilska

  • Series Title: Current Topics in Neurotoxicity

  • DOI: https://doi.org/10.1007/978-3-319-78707-7

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2018

  • Hardcover ISBN: 978-3-319-78706-0Published: 25 April 2018

  • Softcover ISBN: 978-3-030-08769-2Published: 26 December 2018

  • eBook ISBN: 978-3-319-78707-7Published: 16 April 2018

  • Series ISSN: 2363-9563

  • Series E-ISSN: 2363-9571

  • Edition Number: 1

  • Number of Pages: X, 207

  • Topics: Neurosciences, Pharmacology/Toxicology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access