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  • © 2018

Channelopathies in Heart Disease

  • Unique work on channelopathies in cardiac disease, describing cellular mechanisms, scientific methodologies as well as clinical relevance
  • Written by scientists, that contributed significantly to the field
  • Highlights the latest scientific findings and techniques
  • Discusses unmet medical needs, thereby inspiring to further research and development

Part of the book series: Cardiac and Vascular Biology (Abbreviated title: Card. vasc. biol., volume 6)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-vi
  2. Channelopathies in Heart Disease

    • Carol Ann Remme, Dierk Thomas
    Pages 1-5
  3. (Dys)Function of Cardiac Ion Channels

    1. Front Matter

      Pages 7-7
    2. Potassium Channels in the Heart

      • Morten B. Thomsen
      Pages 47-75
    3. Voltage-Gated Calcium Channels and Their Roles in Cardiac Electrophysiology

      • Jordi Heijman, Cristina E. Molina, Niels Voigt
      Pages 77-96
    4. HCN Channels and Cardiac Pacemaking

      • Annalisa Bucchi, Chiara Piantoni, Andrea Barbuti, Dario DiFrancesco, Mirko Baruscotti
      Pages 97-126
    5. Dysregulation of Ionic Homeostasis: Relevance for Cardiac Arrhythmias

      • Claire Hopton, Luigi Venetucci, Miriam Lettieri
      Pages 127-144
  4. Cardiac Channelopathies: Clinical and Genetic Findings

    1. Front Matter

      Pages 145-145
    2. Long and Short QT Syndromes

      • Lia Crotti, Maria-Christina Kotta, Silvia Castelletti
      Pages 147-185
    3. Brugada Syndrome: Current Perspectives

      • Apichai Khongphatthanayothin, Koonlawee Nademanee
      Pages 187-214
    4. Sinus Node Disease and Cardiac Conduction Disease

      • Patrick A. Schweizer
      Pages 215-229
    5. Catecholaminergic Polymorphic Ventricular Tachycardia

      • Riccardo Maragna, Carlo Napolitano
      Pages 231-256
    6. Atrial Fibrillation

      • Ann-Kathrin Rahm, Hugo A. Katus, Dierk Thomas
      Pages 277-322
    7. Genetic Testing for Inheritable Cardiac Channelopathies

      • Florence Kyndt, Jean-Baptiste Gourraud, Julien Barc
      Pages 323-358
  5. Research into Cardiac Channelopathies: New Avenues

    1. Front Matter

      Pages 359-359
    2. Novel Imaging Techniques in Cardiac Ion Channel Research

      • Esperanza Agullo-Pascual, Alejandra Leo-Macias, Donna R. Whelan, Mario Delmar, Eli Rothenberg
      Pages 361-378

About this book

This book provides an expert overview on ion channel-related arrhythmia mechanisms, and describes important advances in our understanding of how ion channel dysfunction causes cardiac disease. Both, scientific findings and clinical implications are presented and discussed by scientists who have considerably contributed to the field.

The book is organized in three parts: part I  treats the molecular and electrophysiological mechanisms of function and dysfunction of ion channels,  part II focuses on genetics and clinical findings, whereas part III describes novel research techniques, the use of stem cells and animal models and provides an outlook on future investigations and applications.

The book is written for scientists in Cardiovascular Biology and Neuroscience and will be of general interest to Medical Doctors in Cardiology, Cardiac Electrophysiology and related disciplines.

 

Editors and Affiliations

  • Department of Cardiology and HCR (Heidelberg Center for Heart Rhythm Disorders), University Hospital Heidelberg, Heidelberg, Germany

    Dierk Thomas

  • Dept. of Clinical & Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    Carol Ann Remme

About the editors

Prof. Dr. med. Dierk Thomas is Associate Professor at the University of Heidelberg and Head of the Cardiac Electrophysiology Department, Medical University Hospital, University of Heidelberg, Germany.

Dr. Carol Ann Remme is Associate Professor and Principal Investigator at the Department of Clinical and Experimental Cardiology, Academic Medical Center, Amsterdam, The Netherlands.

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access