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  • © 2018

Activation of Viruses by Host Proteases

  • Presents recent findings on this topic
  • Deals with all aspects of the role of proteases in virus activation
  • Explores the topic from different points of view

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Softcover Book USD 199.99
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Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
  2. Viral Proteins Activated By Host Proteases

    1. Front Matter

      Pages 1-1
    2. Activation of the Hemagglutinin of Influenza Viruses

      • Summer E. Galloway, Bo Liang, David A. Steinhauer
      Pages 3-26
    3. Proteolytic Activation of Paramyxoviruses and Pneumoviruses

      • Everett Clinton Smith, Rebecca Ellis Dutch
      Pages 27-45
    4. Cleavage of the Glycoprotein of Arenaviruses

      • Antonella Pasquato, Laura Cendron, Stefan Kunz
      Pages 47-70
    5. Priming Time: How Cellular Proteases Arm Coronavirus Spike Proteins

      • Markus Hoffmann, Heike Hofmann-Winkler, Stefan Pöhlmann
      Pages 71-98
    6. Proteolytic Processing of Filovirus Glycoproteins

      • Viktor Volchkov, Hans Dieter Klenk
      Pages 99-108
    7. Proteolytic Activation of Flavivirus Envelope Proteins

      • Franz X. Heinz, Karin Stiasny
      Pages 109-132
  3. Protease Inhibitors

    1. Front Matter

      Pages 277-277
    2. The Antiviral Potential of Host Protease Inhibitors

      • Torsten Steinmetzer, Kornelia Hardes
      Pages 279-325
  4. Back Matter

    Pages 327-335

About this book

This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy.

This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.



Editors and Affiliations

  • Institut für Virologie, Philipps Universität, Marburg, Germany

    Eva Böttcher-Friebertshäuser, Wolfgang Garten

  • Institut für Virologie, Philipps-Universität, Marburg, Germany

    Hans Dieter Klenk

About the editors

Eva Böttcher-Friebertshäuser, Wolfgang Garten, and Hans Dieter Klenk are at the Institute of Virology, Philipps University Marburg, 35043 Marburg, Germany


Bibliographic Information

  • Book Title: Activation of Viruses by Host Proteases

  • Editors: Eva Böttcher-Friebertshäuser, Wolfgang Garten, Hans Dieter Klenk

  • DOI: https://doi.org/10.1007/978-3-319-75474-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2018

  • Hardcover ISBN: 978-3-319-75473-4Published: 31 May 2018

  • Softcover ISBN: 978-3-030-09242-9Published: 14 December 2018

  • eBook ISBN: 978-3-319-75474-1Published: 22 May 2018

  • Edition Number: 1

  • Number of Pages: X, 335

  • Number of Illustrations: 18 b/w illustrations, 53 illustrations in colour

  • Topics: Virology, Enzymology, Protein-Ligand Interactions

Buy it now

Buying options

Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access