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Island of Reil (Insula) in the Human Brain

Anatomical, Functional, Clinical and Surgical Aspects

  • Covers anatomical features and functions as well as surgery and clinical disorders related to the insular cortex

  • Explores both the basic science and advances in radiologic and surgical therapy

  • Written by leading international experts

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Table of contents (31 chapters)

  1. Front Matter

    Pages i-xi
  2. Anatomy of the Human Insula

    1. Front Matter

      Pages 1-1
    2. The Insular Cortex: Histological and Embryological Evaluation

      • Yigit Uyanikgil, Turker Cavusoglu, Servet Celik, Kubilay Dogan Kilic, Mehmet Turgut
      Pages 3-13
    3. Gross Anatomy of the Human Insula

      • Igor Lima Maldonado, Ilyess Zemmoura, Christophe Destrieux
      Pages 15-22
    4. Surgical Anatomy of the Insula

      • Christophe Destrieux, Igor Lima Maldonado, Louis-Marie Terrier, Ilyess Zemmoura
      Pages 23-37
    5. Anatomy of the Insular Arteries

      • Servet Celik, Okan Bilge, Canan Yurttaş, Mehmet Turgut
      Pages 39-53
    6. Anatomy of the Insular Veins

      • Servet Celik, Okan Bilge, Mehmet Turgut, Canan Yurttaş
      Pages 55-69
    7. Middle Longitudinal Fasciculus in the Human Brain from Fiber Dissection

      • Igor Lima Maldonado, Ilyess Zemmoura, Christophe Destrieux
      Pages 71-75
    8. Structural Connectivity of the Insula

      • Jimmy Ghaziri, Dang Khoa Nguyen
      Pages 77-83
    9. Insular Pharmacology

      • Hasan Emre Aydın, İsmail Kaya
      Pages 85-90
    10. Neuroimaging Techniques for Investigation of the Insula

      • Ersen Ertekin, Özüm Tunçyürek, Mehmet Turgut, Yelda Özsunar
      Pages 91-100
    11. Measurements of the Insula Volume Using MRI

      • Niyazi Acer, Mehmet Turgut
      Pages 101-111
    12. Neurocognitive Mechanisms of Social Anxiety and Interoception

      • Yuri Terasawa, Satoshi Umeda
      Pages 113-120
  3. Functions of the Human Insula

    1. Front Matter

      Pages 121-121
    2. Participation of the Insula in Language

      • Alfredo Ardila
      Pages 123-128
    3. Lateralization of the Insular Cortex

      • Michael J. Montalbano, R. Shane Tubbs
      Pages 129-132
    4. Gustatory Areas Within the Insular Cortex

      • Richard J. Stevenson, Heather M. Francis, Cameron J. Ragg
      Pages 133-145
    5. Role of the Insula in Human Cognition and Motivation

      • Oreste de Divitiis, Teresa Somma, D’Urso Giordano, Mehmet Turgut, Paolo Cappabianca
      Pages 147-149
    6. The Anterior Insula and Its Relationship to Autism

      • Seong-Jin Moon, Lara Tkachenko, Erick Garcia-Gorbea, R. Shane Tubbs, Marc D. Moisi
      Pages 157-159

About this book

This book provides an in-depth review of the insula, with emphasis on anatomical, diagnostics, clinical, and surgical features. The insular cortex is involved in a variety of functions, but a comprehensive resource cataloging these functions is not available in the current literature. This book gathers highly informative chapters written and edited by leading international authorities in the field and covers the full range of the insular cortex, approaching it in four main sections: firstly, the embryology and anatomy of the human insula; secondly, the functions of the human insula, including its role in nociception, language, decision making, cognition, emotional awareness etc.; thirdly, clinical disorders related to the insula such as epilepsy, schizophrenia, and Parkinson’s disease; and fourthly, surgical techniques for insular gliomas and temporal lobe epilepsy. This comprehensive reference book will be an ideal source for neurosurgeons, neurologists and neuroanatomists seeking both basic and more advanced information regarding this unique structure in the human brain.

Editors and Affiliations

  • Adnan Menderes University, School of Medicine , Aydın, Turkey

    Mehmet Turgut

  • Ege University, Department of Anatomy, Izmir, Turkey

    Canan Yurttaş

  • Seattle Science Foundation, Seattle, USA

    R. Shane Tubbs

About the editors

Mehmet Turgut, MD, PhD, graduated from the Ege University School of Medicine, İzmir, Turkey and later specialized in neurosurgery in Hacettepe University Hospital, Ankara, Turkey. In 2004, he received his PhD degree from Ege University Health Sciences Institute. He is currently an Associate Professor at the Department of Neurosurgery, Adnan Menderes University School of Medicine. His fields of expertise and research interests are broad and include developmental neuroscience, neuroanatomy, pediatric neurosurgery, infectious diseases of the central nervous system, peripheral nerve surgery, and experimental pinealectomy. Dr. Turgut is an editorial board member for 24 international journals including Central European Neurosurgery, Journal of Pediatric Neurology, and Journal of Neurosciences in Rural Practice and a reviewer for a wide range of international journals and research programs. He has authored and co-authored more than 300 papers published in peer-reviewed journals, as well as over 40 books and book chapters.

Canan Yurttaş, MD, is a Professor of Anatomy at Ege University School of Medicine, İzmir, Turkey. She is the local coordinator between Ege University and EURON, the European Graduate School of Neuroscience and serves as a lecturer at Ege University’s Department of Neuroscience. Her areas of interest include DTI imaging, neurostereology and Klinger’s method of white matter dissection of the nervous system. She has 25 years of teaching and research experience and has authored and co-authored more than 30 papers published in peer-reviewed journals, as well as 5 books and book chapters.

R. Shane Tubbs, MS, PA-C, PhD is a Professor of Anatomy at St. George’s University, Grenada and has honorary professorships at Dundee University and Vanderbilt University.  He is also Chief Scientific Officer and Vice President of the Seattle Science Foundation in Seattle, WA.  Dr. Tubbs’ research interests are centered on “reverse translational anatomy research” where clinical problems are identified and solved with anatomical studies. Dr. Tubbs also serves on the editorial board of 10 anatomical journals and has reviewed for over 100 scientific journals. He has been a visiting professor to major institutions in the US and worldwide. Dr. Tubbs has authored over 20 books and over 50 book chapters. He is an editor for the 41st edition of Gray’s Anatomy and is the editor-in-chief of the journal Clinical Anatomy.

Bibliographic Information

  • Book Title: Island of Reil (Insula) in the Human Brain

  • Book Subtitle: Anatomical, Functional, Clinical and Surgical Aspects

  • Editors: Mehmet Turgut, Canan Yurttaş , R. Shane Tubbs

  • DOI: https://doi.org/10.1007/978-3-319-75468-0

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2018

  • Hardcover ISBN: 978-3-319-75467-3Published: 09 August 2018

  • Softcover ISBN: 978-3-030-09240-5Published: 04 February 2019

  • eBook ISBN: 978-3-319-75468-0Published: 24 July 2018

  • Edition Number: 1

  • Number of Pages: XI, 298

  • Number of Illustrations: 9 b/w illustrations, 48 illustrations in colour

  • Topics: Neurosurgery, Neurology, Neurosciences

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access