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Cardiac Cell Culture Technologies

Microfluidic and On-Chip Systems

  • Microfluidic systems for cardiac cell culture are discussed based on tested cells and the methods of cardiac cell stimulation

  • The use of stem cell stimulation into cardiac cells in microfluidic systems is discussed in the context of electrical, biochemical, physical, and mechanical stimulations

  • Provides an overview of the measurements and data that can be extracted from on-chip systems for use in diagnostics, drug discovery and screening, and clinical therapy

  • Includes supplementary material: sn.pub/extras

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xix
  2. Introduction

    • Elzbieta Jastrzebska, Zbigniew Brzozka
    Pages 1-2
  3. Microfluidic Systems

    • Sandra Skorupska, Elzbieta Jastrzebska, Michal Chudy, Artur Dybko, Zbigniew Brzozka
    Pages 3-21
  4. Lab-on-a-chip Systems for Cellomics—Materials and Technology

    • Dominika Kalinowska, Katarzyna Tokarska, Ilona Grabowska-Jadach, Artur Dybko, Zbigniew Brzozka
    Pages 23-53
  5. Organ-on-a-chip Systems

    • Aleksandra Szuplewska, Michal Chudy, Zbigniew Brzozka
    Pages 55-78
  6. Pluripotent and Mesenchymal Stem Cells—Challenging Sources for Derivation of Myoblast

    • Karolina Archacka, Edyta Brzoska, Maria A. Ciemerych, Areta M. Czerwinska, Iwona Grabowska, Kamil K. Kowalski et al.
    Pages 109-154
  7. Microfluidic Systems for Cardiac Cell Culture—Characterization

    • Elzbieta Jastrzebska, Zbigniew Brzozka
    Pages 155-167
  8. Heart-on-a-chip Systems

    • Magdalena Bulka, Elzbieta Jastrzebska
    Pages 169-199
  9. Cardiac Cell Culture Microtechnologies Based on Stem Cells

    • Anna Kobuszewska, Patrycja Sokolowska, Elzbieta Jastrzebska
    Pages 201-231
  10. Back Matter

    Pages 233-234

About this book

This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center their discussion of the use of stem cell stimulation based on four different types: electrical, biochemical, physical, and mechanical. This book is appropriate for researchers focused on on-chip technologies and heart studies, students in bioengineering and microengineering courses, and a variety of professionals, such as biotechnologists, biomedical engineers, and clinicians working in the cardiac diseases field.

Editors and Affiliations

  • The Chair of Medical Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Warsaw, Poland

    Zbigniew Brzozka, Elzbieta Jastrzebska

About the editors

Zbigniew Brzozka is Professor in the Chair of Medical Biotechnology and Head of the Lab-on-a-Chip group at Warsaw University of Technology.

Elzbieta Jastrzebska is Assistant Professor in the Chair of Medical Biotechnology at Warsaw University of Technology.

Bibliographic Information

  • Book Title: Cardiac Cell Culture Technologies

  • Book Subtitle: Microfluidic and On-Chip Systems

  • Editors: Zbigniew Brzozka, Elzbieta Jastrzebska

  • DOI: https://doi.org/10.1007/978-3-319-70685-6

  • Publisher: Springer Cham

  • eBook Packages: Engineering, Engineering (R0)

  • Copyright Information: Springer International Publishing AG 2018

  • Hardcover ISBN: 978-3-319-70684-9Published: 01 December 2017

  • Softcover ISBN: 978-3-319-88979-5Published: 04 September 2018

  • eBook ISBN: 978-3-319-70685-6Published: 21 November 2017

  • Edition Number: 1

  • Number of Pages: XIX, 234

  • Number of Illustrations: 1 b/w illustrations, 57 illustrations in colour

  • Topics: Biomedical Engineering and Bioengineering, Nanotechnology and Microengineering, Biomedical Engineering/Biotechnology, Cardiology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access