Overview
- Provides new insights on the molecular mechanisms of microbial evolution
- Highlights the relevance and challenges of studying microbial evolution
- Foreword written by Werner Arber (1978 Nobel Prize in Physiology or Medicine)
- Includes supplementary material: sn.pub/extras
Part of the book series: Grand Challenges in Biology and Biotechnology (GCBB)
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Table of contents (15 chapters)
Keywords
About this book
Recent advances in DNA sequencing, high-throughput technologies, and genetic manipulation systems have enabled studies that directly characterize the molecular and genomic bases of evolution, producing data that are making us change our view of the microbial world. The notion that mutations in the coding regions of genomes are, in combination with selective forces, the main contributors to biodiversity needs to be re-examined as evidence accumulates, indicating that many non-coding regions that contain regulatory signals show a high rate of variation even among closely related organisms. Comparative analyses of an increasing number of closely related microbial genomes have yielded exciting insight into the sources of microbial genome variability with respect to gene content, gene order and evolution of genes with unknown functions. Furthermore, laboratory studies (i.e. experimental microbial evolution) are providing fundamental biological insight through direct observation of the evolution process. They not only enable testing evolutionary theory and principles, but also have applications to metabolic engineering and human health.
Overall, these studies ranging from viruses to Bacteria to microbial Eukaryotes are illuminating the mechanisms of evolution at a resolution that Darwin, Delbruck and Dobzhansky could barely have imagined. Consequently, it is timely to review and highlight the progress so far as well as discuss what remains unknown and requires future research. This book explores the current state of knowledge on the molecular mechanisms of microbial evolution with a collection of papers written by authors who are leading experts in the field.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Molecular Mechanisms of Microbial Evolution
Editors: Pabulo H. Rampelotto
Series Title: Grand Challenges in Biology and Biotechnology
DOI: https://doi.org/10.1007/978-3-319-69078-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-69077-3Published: 23 October 2018
Softcover ISBN: 978-3-030-09867-4Published: 25 December 2018
eBook ISBN: 978-3-319-69078-0Published: 12 October 2018
Series ISSN: 2367-1017
Series E-ISSN: 2367-1025
Edition Number: 1
Number of Pages: XIII, 448
Number of Illustrations: 17 b/w illustrations, 54 illustrations in colour
Topics: Microbial Genetics and Genomics, Evolutionary Biology, Applied Microbiology