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PET/MRI in Oncology

Current Clinical Applications

  • Offers a balanced presentation of technical and clinical topics
  • Covers a wide range of oncological applications in a concise and clear style
  • Written by experts with extensive experience in the use of PET/MRI in oncology

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-ix
  2. PET System Technology Designs for Achieving Simultaneous PET/MRI

    • Brian J. Lee, Chen-Ming Chang, Craig S. Levin
    Pages 1-26
  3. MR Pulse Sequences for PET/MRI

    • Peder E. Z. Larson, Valentina Taviani
    Pages 27-39
  4. MRI Contrast Agents

    • Thomas A. Hope
    Pages 41-51
  5. PET/MRI: Attenuation Correction

    • Gaspar Delso, Johan Nuyts
    Pages 53-75
  6. PET/MRI: Motion Correction

    • Ciprian Catana
    Pages 77-96
  7. PET/MRI: Reliability/Reproducibility of SUV Measurements

    • Habib Zaidi, Irene A. Burger
    Pages 97-114
  8. PET/MRI: Safety Considerations

    • Richard K. G. Do, David W. Dick
    Pages 115-130
  9. Imaging of Tumour Heterogeneity: Functional MR Techniques in Oncology

    • Christian Kelly-Morland, Gary Cook, Vicky Goh
    Pages 131-150
  10. Workflow and Protocol Considerations

    • Ambros Beer, Patrick Veit-Haibach
    Pages 151-168
  11. Total-Body PET/MRI in Oncological Applications

    • Ryogo Minamimoto, Valentina Taviani, Shreyas Vasanawala, Andrei Iagaru
    Pages 169-184
  12. PET/MRI in Brain Tumors

    • Ida Sonni, Valentina Garibotto, Andrei Iagaru, Devsmita Das, Tarik Massoud
    Pages 185-222
  13. Neuro: Head and Neck Oncology

    • Martin W. Huellner, Spyros S. Kollias, Gerhard F. Huber, Marcelo A. Queiroz
    Pages 223-248
  14. Lung Nodule Detection Using PET/MRI

    • Paul Flechsig, Esha Baidya Kayal, Amit Mehndiratta, Frederik L. Giesel
    Pages 249-260
  15. PET/MRI in Breast Cancer

    • Claire Tabouret-Viaud, Ismini Mainta, Valentina Garibotto, Diomidis Botsikas, Bénédicte M. A. Delattre, Osman Ratib
    Pages 261-280
  16. Hepatobiliary and Pancreatic Cancer PET/MRI

    • Thomas A. Hope
    Pages 281-290
  17. PET/MRI in Neuroendocrine Tumours

    • Simon Wan, Jamshed Bomanji
    Pages 291-304
  18. Rectal Cancer

    • Ajit H. Goenka, Cristina Nanni, Sudhakar K. Venkatesh
    Pages 305-319
  19. PET/MRI for Gynecological Malignancies

    • Ephraim Parent, Vanessa Sanders, Farrokh Dehdashti, Kathryn Fowler
    Pages 321-339
  20. PET/MRI in Prostate Cancer

    • Ida Sonni, Lucia Baratto, Martin T. Freitag, Frederik Giesel, Matthias Eiber, Andrei Iagaru
    Pages 341-371

About this book

In this book, experts from premier institutions across the world with extensive experience in the field clearly and succinctly describe the current and anticipated uses of PET/MRI in oncology. The book also includes detailed presentations of the MRI and PET technologies as they apply to the combined PET/MRI scanners. The applications of PET/MRI in a wide range of oncological settings are well documented, highlighting characteristic findings, advantages of this dual-modality technique, and pitfalls. Whole-body PET/MRI applications and pediatric oncology are discussed separately. In addition, information is provided on PET technology designs and MR hardware for PET/MRI, MR pulse sequences and contrast agents, attenuation and motion correction, the reliability of standardized uptake value measurements, and safety considerations. The balanced presentation of clinical topics and technical aspects will ensure that the book is of wide appeal. It will serve as a reference for specialists innuclear medicine and radiology and oncologists and will also be of interest for residents in these fields and technologists.

Reviews

“It is an updated and highly didactic text that is able to satisfy all the most important questions of people interested in the subject. … All the chapters are written in a concise and clear style, and are therefore easily understandable by beginners, but still retaining the interest of experts. … The major value of the book is the wide presentation of information achievable by the hybrid tool and by PET and MRI (also including fMRI) alone.” (Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 46, 2019)






“This textbook represents a timely and succinct summary of the current scientific and clinical experience by a panel of world-leading experts on this topic to date. The book is compact and well-balanced. … All the chapters are well-referenced. They are written in language that is unassuming and can be easily understood regardless of its readers’ professional background … . I would strongly recommend this book to anyone interested in the subject.” (Simon Wan, RAD Magazine, August, 2018)



“It would be an asset to any training clinician in the core medical and surgical specialties who intends to pursue a career in oncology and haematology. It will be of particular benefit to training clinical and medical oncologists, who will find this book a useful reference for their future practice.” (Andy Scarsbrook, British Journal of Hospital Medicine, Vol. 19 (6), June, 2018)

Editors and Affiliations

  • Division of Nuclear Medicine and Molecular Imaging, Stanford University, Stanford, USA

    Andrei Iagaru

  • Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, USA

    Thomas Hope

  • Dept. of Nuclear Medicine, University of Zurich, Zurich, Switzerland

    Patrick Veit-Haibach

About the editors

Dr. Iagaru is an Associate Professor of Radiology - Nuclear Medicine and the Co-Chief of the Division of Nuclear Medicine and Molecular Imaging at Stanford University Medical Center. He completed medical school at Carol Davila University of Medicine, Bucharest, Romania, and an internship at Drexel University College of Medicine, Graduate Hospital, in the Department of Medicine in Philadelphia. He began his residency at the University of Southern California (USC) Keck School of Medicine, Los Angeles, in the Division of Nuclear Medicine, where he was the chief resident. Dr. Iagaru finished his residency and completed a PET/CT fellowship at Stanford University's School of Medicine in the Division of Nuclear Medicine. His research interests include PET/MRI and PET/CT for early cancer detection; clinical translation of novel PET radiopharmaceuticals; peptide-based diagnostic imaging and therapy; radioimmunotherapy.
Over the past seven years since joining the faculty at Stanford, Dr. Iagaru has received several awards including the Society of Nuclear Medicine (SNM) 2009 Image of the Year Award; American College of Nuclear Medicine (ACNM) Mid-Winter Conference 2010 Best Essay Award; 2009 Western Regional SNM Scientist Award; 2011 SNM Nuclear Oncology Council Young Investigator Award; and a Stanford Cancer Center 2009 Developmental Cancer Research Award in Translational Science. Dr. Iagaru presented more than 90 abstracts at national and international meetings and published more than 60 papers in peer-reviewed journals, as well as 7 book chapters.

Dr. Veit-Haibach is an Associate Professor of Radiology  and Nuclear Medicine at the University Hospital in Zurich, Switzerland. He currently serves as the Section Head of the PET/CT-MR and PET/MR Unit in Zurich. He completed medical school at the University in Essen, Germany. During medical school, he completed internships/trainings in Germany, Switzerland, New Zealand and the United States. He started 100 papers in peer-reviewed journals, 7 book chapters and already served as a guest editor for the Seminar in Nuclear Medicine and the European Journal of Nuclear Medicine and Molecular Imaging.


Dr. Thomas Hope is an Assistant Professor in Residence in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco (UCSF), with appointments in the Abdominal Imaging and Nuclear Medicine sections. He completed medical school at Stanford University and completed his residency in Diagnostic Radiology at UCSF. He subsequently returned to Stanford University to complete fellowships in Body MRI and PET/CT. He currently serves as the Director of MRI at the San Francisco VA Medical Center and as co-Director of PET/MRI at UCSF.  Additionally, he is the Chair of the PET/MRI Task Force within the PET Center of Excellence for the Society of Nuclear Medicine and Molecular Imaging, as well as serves on the steering committee for LI-RADS (Liver Imaging Reporting and Data System). His research interests include the application of novel MRI techniques, translation of novel PET radiopharmaceuticals, and the development and clinical application of PET/MRI. Dr. Hope has published over 30 papers, and was awarded the Wylie J. Dodds Research Award from the Society of Abdominal Radiology for his evaluation of DOTA-TOC PET/MRI, as well as the Presidents Circle Research Resident Grant and the Roentgen Resident/Fellow Research Award from the Radiological Society of North America.

Bibliographic Information

  • Book Title: PET/MRI in Oncology

  • Book Subtitle: Current Clinical Applications

  • Editors: Andrei Iagaru, Thomas Hope, Patrick Veit-Haibach

  • DOI: https://doi.org/10.1007/978-3-319-68517-5

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG 2018

  • Hardcover ISBN: 978-3-319-68516-8Published: 02 February 2018

  • Softcover ISBN: 978-3-319-88615-2Published: 06 June 2019

  • eBook ISBN: 978-3-319-68517-5Published: 23 January 2018

  • Edition Number: 1

  • Number of Pages: IX, 433

  • Number of Illustrations: 24 b/w illustrations, 71 illustrations in colour

  • Topics: Nuclear Medicine, Oncology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access