Molecular and Functional Insights Into the Pulmonary Vasculature

1. Front Matter

   Pages i-v

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2. Transcription Factors Regulating Embryonic Development of Pulmonary Vasculature

   • Craig Bolte, Jeffrey A. Whitsett, Tanya V. Kalin, Vladimir V. Kalinichenko

   Pages 1-20

3. Comparative View of Lung Vascular Endothelium of Cattle, Horses, and Water Buffalo

   • David Schneberger, Ram S. Sethi, Baljit Singh

   Pages 21-39

4. The Pulmonary Vascular Barrier: Insights into Structure, Function, and Regulatory Mechanisms

   • Kaushik Parthasarathi

   Pages 41-61

5. Pulmonary Endothelial Cell Apoptosis in Emphysema and Acute Lung Injury

   • Eboni Chambers, Sharon Rounds, Qing Lu

   Pages 63-86

This book provides a comprehensive review of the structure, function and pathophysiology of the pulmonary vasculature. Emerging evidence reveals the multifaceted roles played by the pulmonary vasculature. To reflect those roles, the individual chapters address topics ranging from pulmonary blood vessel development to vascular endothelial apoptosis, and delve deeply into our current understanding of various aspects of the pulmonary vasculature.

• Apoptotic mechanisms
• Embryonic development
• Intercellular junctions
• Leukocyte-endothelial interactions
• Mitochondria-dependent signaling
• Pulmonary vasculature

• Department of Physiology, University of Tennessee Health Science Center, Memphis, USA

  Kaushik Parthasarathi

Kaushik Parthasarathi obtained his Master’s degree from Virginia Commonwealth University, Richmond, Virginia and his doctoral degree from Pennsylvania State University, University Park, Pennsylvania. He completed his post-doctoral work at Columbia University, New York City, where he then continued as a Research Scientist. He subsequently joined the University of Tennessee Health Science Center, Memphis, where he is currently an Associate Professor of Physiology. His research interests include connexin-mediated mechanisms in inflammation and leukocyte-endothelial interactions. His studies chiefly employ intravital and optical fluorescence microscopy, as well as organ preparations. Prof. Parthasarathi is also involved in graduate-level medical education and a member of the Department of Medical Education.

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