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Right Ventricular Physiology, Adaptation and Failure in Congenital and Acquired Heart Disease

  • Book
  • © 2018

Overview

Editors:
  1. Mark K. Friedberg

    1. Paediatric Cardiology, Labatt Family Heart Center Hospital for Sick Children, Toronto, Canada

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  2. Andrew N. Redington

    1. Heart Institute, Cincinnati Children’s Hosp Med Center, Cincinnati, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Incorporates basic and clinical concepts with extensive use of translational research methodology

  • Contains extensive discussion of the future directions/concepts in right ventricular medicine/research

  • Integrates topics relevant to both pediatric and adult cardiologists/investigators

  • Includes supplementary material: sn.pub/extras

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-x
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  2. Embryological Origins: How Does the Right Ventricle Form

    • Paul Delgado-Olguín
    Pages 1-17

  3. How Does the Pressure-Overloaded Right Ventricle Adapt and Why Does It Fail? Macro-and Micro-Molecular Perspectives

    • Norbert F. Voelkel
    Pages 19-27

  4. Molecular Aspects of Right Ventricular Adaptation to Stress

    • Sushma Reddy, Daniel Bernstein
    Pages 29-40

  5. Genetic Variation and Outcomes in Right Ventricular Congenital Heart Disease

    • Seema Mital
    Pages 41-51

  6. Ventricular-Vascular Coupling in the Pulmonary Circulation

    • Nicholas E. Hobson, Kendall S. Hunter
    Pages 53-68

  7. Right–Left Ventricular Interactions in RV Afterload and Preload

    • Mark K. Friedberg
    Pages 69-79

  8. Computational Study on the Cardiovascular System: Ventricular–Ventricular Interaction and Right Ventricular Failure in Pulmonary Arterial Hypertension

    • Tammo Delhaas, Theo Arts, Yvette Koeken, Joost Lumens, Georgina Palau-Caballero, John Walmsley
    Pages 81-91

  9. Can the Right Ventricle Support the Failing Left Ventricle?

    • Dietmar Schranz
    Pages 93-97

  10. Echocardiographic Assessment of the Right Ventricle

    • Luc L. Mertens
    Pages 99-111

  11. Magnetic Resonance Assessment of RV Remodeling and Function

    • Lars Grosse-Wortmann, Adam L. Dorfman
    Pages 113-128

  12. Pulmonary Hypertension in Chronic Neonatal Lung Disease: Mechanisms and Targets

    • Robert P. Jankov, A. Keith Tanswell
    Pages 129-145

  13. Right Ventricular Function in Ebstein’s Malformation

    • Jan Marek, Marina L. Hughes, Victor Tsang
    Pages 147-159

  14. Ebstein’s Malformation: Does Echocardiographic Assessment Determine Surgical Repair?

    • Norman H. Silverman
    Pages 161-183

  15. Single Right Ventricular Function and Failure in the Fontan Circulation

    • Andrew N. Redington
    Pages 185-192

  16. Right Ventricular Dysfunction Post-Heart Transplantation

    • Jacob Mathew, Anne I. Dipchand
    Pages 193-216

  17. Medical Therapy for Chronic Right Ventricular Failure in Congenital Heart Disease

    • S. Lucy Roche
    Pages 217-231

  18. Transcatheter Pulmonary Valve Replacement: Impact on Management

    • Harsimran S. Singh, Lee Benson
    Pages 233-245

  19. Can Surgeons Preserve Right Ventricular Function in Hypoplastic Left Heart Syndrome?

    • Christoph Haller, Christopher A. Caldarone
    Pages 247-259

  20. Back Matter

    Pages 261-267
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Keywords

About this book

This book spans topics in both congenital and acquired right heart disease providing readers with detailed information on the physiology, anatomy and myocardial mechanics of the right ventricle (RV), while describing the use of echo and MRI imaging to diagnose, and new developments in surgery and cardiac catheterization to treat.

Right Ventricular Physiology, Adaptation and Failure in Congenital and Acquired Heart Disease includes extensive discussion of RV-pulmonary interactions, pulmonary hypertension and ventricular-ventricular interactions, including specific topics in embryology, fetal RV function, RV mechanics, pathophysiology of RV adaptation/ failure, molecular aspects of RV dysfunction, congenital heart disease, pulmonary arterial hypertension, pulmonary valve replacement, stem cell and future therapies.​ It is thus important reading for all cardiovascular medicine professionals, but especially pediatric cardiologists and surgeons, those who manage t

hese patients in the cardiac care unit and investigators studying the RV. 

Editors and Affiliations

  • Paediatric Cardiology, Labatt Family Heart Center Hospital for Sick Children, Toronto, Canada

    Mark K. Friedberg

  • Heart Institute, Cincinnati Children’s Hosp Med Center, Cincinnati, USA

    Andrew N. Redington

About the editors

Mark Friedberg trained as a pediatric cardiologist at the Lucile Packard Children’s Hospital at Stanford in California where he also completed a senior fellowship in pediatric echocardiography and cardiac imaging. At Stanford he was awarded a Glaser Pediatric Research Network fellowship for the years 2005-6. Dr Friedberg joined the Hospital for Sick Children in Toronto and became an assistant professor at the University of Toronto in 2006 where he is currently a staff physician in pediatric and fetal echocardiography. He was appointed as an associate scientist to the Sickkids research institute in 2012 and his lab investigates ventricular-ventricular interactions and mechanisms of biventricular dysfunction in increased RV afterload. His research interests include assessment of ventricular-ventricular interactions, ventricular function, especially RV function in pediatric congenital and acquired heart disease, tissue Doppler and deformation imaging in children and assessment of mechanical dyssynchrony and biventricular pacing in children. Andrew Redington's research interests include ventricular function, integrated physiology of congenital heart disease, and the pathophysiology of late postoperative functional decline. He led a Leducq Transatlantic Research Network of Excellence investigating the biology of remote ischemic preconditioning. He has co-edited seven textbooks. Dr. Redington was awarded a British Heart Foundation Research Scholarship and subsequently received his Doctorate of Medicine in 1988 (UK). He was appointed Consultant Paediatric Cardiologist at the Royal Brompton Hospital, London in 1990, became a fellow of the Royal College of Physicians (UK) in 1994, and became a full professor in the University of London in 1995. In 1998, he transferred his clinical practice and research team to Great Ormond Street Hospital in London. He moved to Canada in August 2001, to take the position of Head of Cardiology at The Hospital for Sick Children, Toronto.

Bibliographic Information

  • Book Title: Right Ventricular Physiology, Adaptation and Failure in Congenital and Acquired Heart Disease

  • Editors: Mark K. Friedberg, Andrew N. Redington

  • DOI: https://doi.org/10.1007/978-3-319-67096-6

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG 2018

  • Hardcover ISBN: 978-3-319-67094-2Published: 05 January 2018

  • Softcover ISBN: 978-3-319-88376-2Published: 04 June 2019

  • eBook ISBN: 978-3-319-67096-6Published: 19 December 2017

  • Edition Number: 1

  • Number of Pages: X, 267

  • Number of Illustrations: 26 b/w illustrations, 72 illustrations in colour

  • Topics: Cardiology, Human Physiology, Cardiac Surgery

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