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Peptides and Peptide-based Biomaterials and their Biomedical Applications

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  • © 2017

Overview

  • Fast-moving and rapidly expanding research area, which promises to be one of the most significant fields of research in applied biomedicine
  • Highlights new developments in the applications of peptide and peptide-based biomaterials in biomedicine
  • Introduces readers to direct applications and translational research at the interface between materials science, protein chemistry and biomedicine

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1030)

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Table of contents (13 chapters)

Keywords

About this book

Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.

Editors and Affiliations

  • Department of Chemistry and Biomolecular Sciences, Macquarie University, North Ryde, Australia

    Anwar Sunna, Peter L. Bergquist

  • Biomolecular Discovery and Design, Research Centre, Macquarie University, North Ryde, Australia

    Andrew Care

About the editors

Anwar Sunna is an Associate Professor in the Department of Chemistry and Biomolecular Sciences at Macquarie University (MQ), Sydney, Australia. He obtained a PhD from the Hamburg University of Technology in Germany. He was manager of the Environmental Biotechnology Co-operative Research Centre at MQ and later was the recipient of the prestigious Vice-Chancellor's Innovation Fellowship. His recent research has been on the interaction between biomolecules and inorganic compounds including new synthetic peptide linkers with applications in the functionalisation of nanoparticles, bioimaging and cancer therapy. Anwar is a member of the MQ Biomolecular Discovery and Design Research Centre, MQ Biosecurity Futures Research Centre, Australian Research Council (ARC) Training Centre for Molecular Technology in the Food Industry and the ARC Centre of Excellence for Nanoscale BioPhotonics. He is also one of the directors of Synthetic Biology Australasia.


Andrew Careis a Research Fellow in the ARC Centre of Excellence for Nanoscale BioPhotonics, a transdisciplinary research centre that aims to develop innovative nanotechnologies to investigate complex living systems. He obtained his PhD from Macquarie University (MQ) in Sydney, Australia. Andrew is also a member of both the MQ Biomolecular Discovery and Design Research Centre and the MQ BioFocus Research Centre. His current research is focused on the development of engineered biomolecules, including solid-binding peptides, to control the self-assembly and biofunctionalisation of materials and biomolecules in a range of biomedical and biotechnological applications.


Peter Bergquist is Emeritus Professor in the Biomolecular Discovery and Design Research Centre at Macquarie University and Emeritus Professor in the Department of Molecular Medicine & Pathology at The University of Auckland Medical School. He has a PhD and DSc from the University of Auckland in New Zealand andhas been a Postdoctoral Fellow and Research Fellow at Harvard Medical School, Yale and Oxford Universities and a Visiting Fellow at New York University School of Medicine. His recent publications reflect research performed with the Environmental Biotechnology Co-operative Research Centre in Australia and he developed research expertise in gas phase catalysis and biofunctionalisation of inorganic matrices containing silica. He has been on the editorial boards of several significant journals such as Applied and Environmental Microbiology and Journal of Bacteriology.

Bibliographic Information

  • Book Title: Peptides and Peptide-based Biomaterials and their Biomedical Applications

  • Editors: Anwar Sunna, Andrew Care, Peter L. Bergquist

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-319-66095-0

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017

  • Hardcover ISBN: 978-3-319-66094-3Published: 16 November 2017

  • Softcover ISBN: 978-3-319-88174-4Published: 29 August 2018

  • eBook ISBN: 978-3-319-66095-0Published: 26 October 2017

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIII, 300

  • Number of Illustrations: 37 b/w illustrations, 74 illustrations in colour

  • Topics: Molecular Medicine, Protein-Ligand Interactions, Biomaterials

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