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  • Textbook
  • © 2017

A Mathematical Approach to Protein Biophysics

  • Exercises included at the end of every chapter
  • Mixes protein biology, mathematics, and computing, supporting a multidisciplinary class
  • Includes detailed notes section and glossary
  • Explains many protein features from a more in-depth perspective
  • Includes supplementary material: sn.pub/extras

Part of the book series: Biological and Medical Physics, Biomedical Engineering (BIOMEDICAL)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xi
  2. Understanding Proteins as Digital Widgets

    • L. Ridgway Scott, Ariel Fernández
    Pages 1-6
  3. Digital Rules for Proteins

    • L. Ridgway Scott, Ariel Fernández
    Pages 7-29
  4. Electrostatic Forces

    • L. Ridgway Scott, Ariel Fernández
    Pages 31-46
  5. Protein Basics

    • L. Ridgway Scott, Ariel Fernández
    Pages 47-64
  6. Protein Structure

    • L. Ridgway Scott, Ariel Fernández
    Pages 65-84
  7. Hydrogen Bonds

    • L. Ridgway Scott, Ariel Fernández
    Pages 85-97
  8. Composition of Protein–Protein Interfaces

    • L. Ridgway Scott, Ariel Fernández
    Pages 99-113
  9. Wrapping Electrostatic Bonds

    • L. Ridgway Scott, Ariel Fernández
    Pages 115-136
  10. Stickiness of Dehydrons

    • L. Ridgway Scott, Ariel Fernández
    Pages 137-145
  11. Electrostatic Force Details

    • L. Ridgway Scott, Ariel Fernández
    Pages 147-176
  12. Dehydrons in Protein Interactivity

    • L. Ridgway Scott, Ariel Fernández
    Pages 177-190
  13. Aromatic Interactions

    • L. Ridgway Scott, Ariel Fernández
    Pages 191-198
  14. Antibody–Antigen Complexes

    • L. Ridgway Scott, Ariel Fernández
    Pages 199-204
  15. Peptide Bond Rotation

    • L. Ridgway Scott, Ariel Fernández
    Pages 205-212
  16. Continuum Equations for Electrostatics

    • L. Ridgway Scott, Ariel Fernández
    Pages 213-234
  17. Wrapping Technology

    • L. Ridgway Scott, Ariel Fernández
    Pages 235-246
  18. Epilogue and Future Perspectives

    • L. Ridgway Scott, Ariel Fernández
    Pages 247-250
  19. Units

    • L. Ridgway Scott, Ariel Fernández
    Pages 251-261
  20. Notes

    • L. Ridgway Scott, Ariel Fernández
    Pages 263-263

About this book

This book explores quantitative aspects of protein biophysics and attempts to delineate certain rules of molecular behavior that make atomic scale objects behave in a digital way.  This book will help readers to understand how certain biological systems involving proteins function as digital information systems despite the fact that underlying processes are analog in nature.

The in-depth explanation of proteins from a quantitative point of view and the variety of level of exercises (including physical experiments) at the end of each chapter will appeal to graduate and senior undergraduate students in mathematics, computer science, mechanical engineering, and physics, wanting to learn about the biophysics of proteins.

L. Ridgway Scott has been Professor of Computer Science and of Mathematics at the University of Chicago since 1998, and the Louis Block Professor since 2001.  He obtained a B.S. degree (Magna Cum Laude) from Tulane University in 1969 and a PhD degree in Mathematics from the Massachusetts Institute of Technology in 1973.  Professor Scott has published over 130 papers and three books, extending over biophysics, parallel computing and fundamental computing aspects of structural mechanics, fluid dynamics, nuclear engineering, and computational chemistry.

Ariel Fernández (born Ariel Fernández Stigliano) is an Argentinian-American physical chemist and mathematician. He obtained his Ph. D. degree in Chemical Physics from Yale University and held the Karl F. Hasselmann Endowed Chair Professorship in Bioengineering at Rice University. He is currently involved in research and entrepreneurial activities at various consultancy firms. Ariel Fernández authored three books on translational medicine and biophysics, and published 360 papers in professional journals. He holds two patents in the field of biotechnology.

Reviews

“The book is built in a textbook-like manner, each chapter being followed by exercises to reinforce the concepts presented throughout. Also included is a comprehensive list of references offering multiple options for future reading. The style of the book makes it accessible to a wide range of audiences from students to established researchers. Although written with a specialised audience in mind, the numerous examples make it accessible to researchers with multidisciplinary backgrounds.” (Irina Ioana Mohorianu, zbMATH 1390.92003, 2018)  

Authors and Affiliations

  • Departments of Computer Science and Mathematics, Institute for Biophysical Dynamics, Computation Institute, University of Chicago, Chicago, USA

    L. Ridgway Scott

  • IAM – Argentine Institute of Mathematics, INQUISUR – Chemistry Institute, CONICET – National Research Council, Buenos Aires, Argentina

    Ariel Fernández

About the authors

L. Ridgway Scott has been Professor of Computer Science and of Mathematics at the University of Chicago since 1998, and the Louis Block Professor since 2001.  He obtained a B.S. degree (Magna Cum Laude) from Tulane University in 1969 and a PhD degree in Mathematics from the Massachusetts Institute of Technology in 1973.  Professor Scott has published over 130 papers and three books, extending over biophysics, parallel computing and fundamental computing aspects of structural mechanics, fluid dynamics, nuclear engineering, and computational chemistry.

Ariel Fernández (born Ariel Fernández Stigliano) is an Argentinian-American physical chemist and mathematician. He obtained his Ph. D. degree in Chemical Physics from Yale University and held the Karl F. Hasselmann Endowed Chair Professorship in Bioengineering at Rice University. He is currently involved in research and entrepreneurial activities at various consultancy firms. Ariel Fernández authored three books on translational medicine and biophysics, and published 360 papers in professional journals. He holds two patents in the field of biotechnology.

Bibliographic Information

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access