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Precision Molecular Pathology of Bladder Cancer

  • Book
  • © 2018

Overview

Editors:
  1. Donna E. Hansel

    1. Department of Pathology, University of California San Diego, San Diego, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Seth P. Lerner

    1. Scott Department of Urology, Baylor College of Medicine, Houston, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Summarizes the current and emerging concepts in molecular pathology of bladder cancer
  • Written at a level that will be understandable to residents, physicians, other members of the health care team, and patients
  • Written by experts in the field?

Part of the book series: Molecular Pathology Library (MPLB)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-ix
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  2. Molecular Pathology of Bladder Cancer: Current Understanding and Application

    1. Front Matter

      Pages 1-1
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    2. Risk Factors and Molecular Features Associated with Bladder Cancer Development

      • Anirban P. Mitra, Georg Bartsch Jr., Richard J. Cote
      Pages 3-28

    3. Grading, Staging, and Morphologic Risk Stratification of Bladder Cancer

      • Brian D. Robinson, Francesca Khani
      Pages 29-42

    4. Genomic Assessment of Muscle-Invasive Bladder Cancer: Insights from the Cancer Genome Atlas (TCGA) Project

      • Jaegil Kim, Gordon Robertson, Rehan Akbani, Seth P. Lerner, John N. Weinstein, Gad Getz et al.
      Pages 43-64

    5. Molecular Alterations in the Pathogenesis of Bladder Cancer Subtypes and Urothelial Carcinoma Variants

      • Hikmat Al-Ahmadie, Gopa Iyer
      Pages 65-83

    6. Treatment Paradigms in Bladder Cancer: Clinical Implications of Histological and Molecular Analysis

      • Mehrad Adibi, Colin P. Dinney
      Pages 85-101

    7. Requisite for Collection and Distribution of Tissue and Fluid Specimens for Molecular Diagnostics and Discovery in Bladder Cancer

      • Adrie van Bokhoven, M. Scott Lucia
      Pages 103-116

    8. Diagnostic, Prognostic, and Predictive Biomarkers on Bladder Tissue and Blood

      • Ryan Hutchinson, Yair Lotan
      Pages 117-136

    9. Urine Cytology and Existing Urinary Biomarkers for Bladder Cancer

      • Thomas A. Longo, Steven C. Brousell, Brant A. Inman
      Pages 137-155

  3. Emerging Concepts in the Molecular Basis of Bladder Cancer Diagnosis and Therapy

    1. Front Matter

      Pages 157-157
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    2. Molecular Targeted Therapy of Bladder Cancer

      • Elizabeth R. Kessler, Dan Theodorescu, Thomas W. Flaig
      Pages 159-180

    3. Response to Immunotherapy: Application of Molecular Pathology to Predict Successful Response

      • Noah M. Hahn, Donna E. Hansel
      Pages 181-194

    4. Emerging Molecular Approaches in the Analysis of Urine in Bladder Cancer Diagnosis

      • James P. Solomon, A. Karim Kader, Donna E. Hansel
      Pages 195-207

    5. Stromal Contributions to Tumor Progression in Urothelial Carcinoma of the Bladder

      • Morgan Cowan, Daniel Miller, Alexander S. Baras
      Pages 209-220

    6. Modeling Bladder Cancer with Genetic Engineering: Fidelity of Human-to-Laboratory Models

      • Xue-Ru Wu
      Pages 221-237

  4. Back Matter

    Pages 239-243
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Keywords

About this book

This succinct yet comprehensive volume describes current and emerging concepts in molecular pathology of bladder cancer. Divided into two distinct sections, the first part focuses on the general principles of molecular findings in bladder cancer, while the second part focuses on the molecular changes associated with specific histologic subtypes. The volume also addresses such topics as molecular alterations in non-invasive and invasive disease, including bladder cancer variants as appropriate, emerging molecular classifiers of bladder cancer, and molecular associations to outcome and treatment. Written by experts in the field, Precision Molecular Pathology of Bladder Cancer is a valuable resource for those in the urologic community, including urologic pathologists, urologists, urologic oncologists and radiation oncologists, who treat and manage bladder cancer.

Editors and Affiliations

  • Department of Pathology, University of California San Diego, San Diego, USA

    Donna E. Hansel

  • Scott Department of Urology, Baylor College of Medicine, Houston, USA

    Seth P. Lerner

About the editors

Donna E. Hansel MD PhD
Professor, UCSD Department of Pathology
Chief, Division of Anatomic Pathology
9500 Gilman Drive, MC 0612
La Jolla, CA 92093





Seth P. Lerner, MD, FACS
Professor, Scott Department of Urology
Beth and Dave Swalm Chair in Urologic Oncology 
Director of Urologic Oncology
Director of the Multidisciplinary Bladder Cancer Program
Faculty Group Practice Medical Director 
Co-Editor in Chief Bladder Cancer
Baylor College of Medicine Medical Center
7200 Cambridge, MC BCM380 
Houston, Texas  77030


Bibliographic Information

  • Book Title: Precision Molecular Pathology of Bladder Cancer

  • Editors: Donna E. Hansel, Seth P. Lerner

  • Series Title: Molecular Pathology Library

  • DOI: https://doi.org/10.1007/978-3-319-64769-2

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG 2018

  • Hardcover ISBN: 978-3-319-64767-8Published: 18 January 2018

  • Softcover ISBN: 978-3-319-87867-6Published: 04 June 2019

  • eBook ISBN: 978-3-319-64769-2Published: 05 January 2018

  • Series ISSN: 1935-987X

  • Series E-ISSN: 1935-9888

  • Edition Number: 1

  • Number of Pages: IX, 243

  • Number of Illustrations: 2 b/w illustrations, 38 illustrations in colour

  • Topics: Pathology, Urology, Oncology

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