Editors:
First comprehensive text on acute promyelocytic leukemia in the last ten years
Summarizes historical, current, and future treatment strategies
Highlights the most recent therapeutic recommendations for relapsed disease
Written by top experts in the field
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Table of contents (21 chapters)
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Front Matter
About this book
This book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO. The text covers major topics such as the pathophysiology of APL coagulopathy, biologic and clinical differences between children and adults with APL, and the role of minimal residual disease monitoring. Additionally, the book summarizes historical, current, and future treatment strategies in both adults and children, while highlighting the most recent therapeutic recommendations for relapsed disease and the evolving indications for autologous and allogeneic stem cell transplant. This volume also features chapters focusing on secondary APL and therapy, late effects, rare presentations such as APL in the elderly and during pregnancy, and rare APL variants that may represent therapeutic challenges.
Written by top experts in the field, Acute Promyelocytic Leukemia: A Clinical Guide is a valuable resource for clinicians and researchers who treat and investigate this disease in children and adults.Reviews
Editors and Affiliations
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Division of Hematology/Oncology, The Hospital for Sick Children and University of Toronto, Toronto, Canada
Oussama Abla
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Department of Hematology, University of Tor Vergata, Rome, Italy
Francesco Lo Coco
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Department of Medicine, Hospital Universitari i Politecnic La Fe, University of Valencia, Valencia, Spain
Miguel A. Sanz
About the editors
Oussama Abla, MD
The Hospital for Sick Children and University of Toronto
Division of Hematology/Oncology
Toronto, ON
Canada
Francesco Lo-Coco, MD
Professor of Hematology
University of Tor VergataRome
Italy
Miguel A. Sanz, MD
Centro de Investigación Biomédica en Red de Cáncer
Madrid
Spain
Bibliographic Information
Book Title: Acute Promyelocytic Leukemia
Book Subtitle: A Clinical Guide
Editors: Oussama Abla, Francesco Lo Coco, Miguel A. Sanz
DOI: https://doi.org/10.1007/978-3-319-64257-4
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-64256-7Published: 11 May 2018
Softcover ISBN: 978-3-030-09713-4Published: 01 February 2019
eBook ISBN: 978-3-319-64257-4Published: 25 April 2018
Edition Number: 1
Number of Pages: XII, 274
Number of Illustrations: 10 b/w illustrations, 29 illustrations in colour
Topics: Hematology, Oncology