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Early Phase Cancer Immunotherapy

  • Book
  • © 2018

Overview

Editors:
  1. Sandip Pravin Patel

    1. Division of Hematology/Oncology Department of Medicine, University of California, San Diego Moores Cancer Center, La Jolla, USA

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  2. Razelle Kurzrock

    1. Division of Hematology/Oncology Department of Medicine, University of California, San Diego Moores Cancer Center, La Jolla, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Focuses on a state-of-the-art review of early phase clinical trials for cancer immunotherapy
  • Discusses about biomarker selection and combinatorial strategies
  • Discusses about safety/toxicity determination of Phase 2 dosing, endpoints in the setting of psuedoprogession and histology selection as they relate to early phase cancer immunotherapy
  • Features chapters written by internationally-known experts in the field

Part of the book series: Current Cancer Research (CUCR)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Primer on Cancer Immunotherapy and the Targeting of Native Proteins

    • Valentin Barsan, Paul C. Tumeh
    Pages 1-28

  3. Pharmacokinetics and Pharmacodynamics of Immunotherapy

    • Lisa H. Lam, Swan D. Lin, Ji Sun
    Pages 29-67

  4. Immunotherapeutic Biomarkers and Selection Strategies

    • Young Kwang Chae, Timothy J. Taxter, Ludimila L. Cavalcante, Francis J. Giles
    Pages 69-114

  5. Radiographic Evaluation of Immunotherapy

    • Jennifer Feneis, Seth Kligerman, Elizabeth Weihe
    Pages 115-131

  6. Cellular Therapy

    • Aaron M. Goodman, Tiffany N. Tanaka, Dan S. Kaufman
    Pages 133-184

  7. Combinatorial Checkpoint Blockade Immunotherapy and Radiation

    • Sangwoo Shawn Kim, Andrew Sharabi
    Pages 185-197

  8. Combinatorial Immunotherapy and Chemotherapy

    • Christin B. DeStefano, Stephen V. Liu
    Pages 199-218

  9. Immune Checkpoint Combinations with Inflammatory Pathway Modulators

    • N. DeVito, M. A. Morse, B. Hanks, J. M. Clarke
    Pages 219-241

  10. Combinations of Genomically and Immune-Targeted Therapies in Early-Phase Clinical Trials

    • Maulik Patel, Sandip Pravin Patel, Razelle Kurzrock
    Pages 243-280

  11. Thoracic Immunotherapy

    • Peter Vu, Lyudmila Bazhenova
    Pages 281-305

  12. Melanoma Immunotherapy

    • Gregory A. Daniels
    Pages 307-331
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Keywords

About this book

This volume, a state-of-the-art review of early phase clinical trials for cancer immunotherapy, discusses biomarker selection, combinatorial strategies and their safety or toxicity, determination of Phase 2 dosing, endpoints in the setting of radiographic pseudoprogression, histology selection, and novel immunotherapeutics as they relate to early phase cancer immunotherapy.

Editors and Affiliations

  • Division of Hematology/Oncology Department of Medicine, University of California, San Diego Moores Cancer Center, La Jolla, USA

    Sandip Pravin Patel, Razelle Kurzrock

About the editors

Razelle Kurzrock, MD, is Senior Deputy Director for Clinical Science, Chief, Division of Hematology & Oncology, Murray Professor of Medicine, Director, Center for Personalized Cancer Therapy & Clinical Trials Office, University of California, San Diego.

Sandip Patel, MD, is Assistant Professor, Cancer Immunotherapy Program, Experimental Therapeutics (Phase 1 Program), Thoracic Oncology, Division of Hematology & Oncology and Center for Personalized Cancer Therapy, UC San Diego Moores Cancer Center.

Bibliographic Information

  • Book Title: Early Phase Cancer Immunotherapy

  • Editors: Sandip Pravin Patel, Razelle Kurzrock

  • Series Title: Current Cancer Research

  • DOI: https://doi.org/10.1007/978-3-319-63757-0

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG 2018

  • Hardcover ISBN: 978-3-319-63756-3Published: 10 November 2017

  • Softcover ISBN: 978-3-319-87628-3Published: 28 August 2018

  • eBook ISBN: 978-3-319-63757-0Published: 03 November 2017

  • Series ISSN: 2199-2584

  • Series E-ISSN: 2199-2592

  • Edition Number: 1

  • Number of Pages: XI, 331

  • Number of Illustrations: 9 b/w illustrations, 15 illustrations in colour

  • Topics: Cancer Research

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