Overview
Sets out the main principles of oncoimmunology
Examines the latest advances and their implications for clinical practice
Focuses especially on drugs with FDA/EMA approvals and breakthrough status
Represents a landmark educational resource of wide appeal to medical students, practitioners, and researchers
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Table of contents (43 chapters)
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Front Matter
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Fundamentals in I-O
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Front Matter
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Breakthrough Status
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Front Matter
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Keywords
About this book
In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals.
Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.
Reviews
Editors and Affiliations
About the editors
Guido Kroemer obtained his MD in 1985 from the University of Innsbruck (Austria) and his PhD in molecular biology in 1992 from the Autonomous University of Madrid (Spain). He is currently a professor at the Faculty of Medicine of the University of Paris Descartes/Paris V, Director of the INSERM Unit “Apoptosis, Cancer and Immunity”, Director of the Metabolomics and Cell Biology platforms of the Gustave Roussy Cancer Campus (Villejuif-Grand Paris), and a practitioner at the Hôpital Européen Georges-Pompidou in Paris. He is also Director of the Paris Alliance of Cancer Research Institutes (PACRI) and the LabEx “Immuno-Oncology”. He is best known for the discoveries that mitochondrial membrane permeabilization constitutes a decisive step in regulated cell death; that autophagy is a cytoprotective mechanism with lifespan-extending effects; and that anticancer therapies are successful only if they stimulate tumor-targeting immune responses. He has received a number of awards, including the Descartes Prize of the European Union, the Dautrebande Prize (Belgian Royal Academy of Medicine), the Léopold Griffuel Prize (French Association for Cancer Research), and The 2017 Charles Rodolphe Brupbacher Prize for Cancer Research.
Bibliographic Information
Book Title: Oncoimmunology
Book Subtitle: A Practical Guide for Cancer Immunotherapy
Editors: Laurence Zitvogel, Guido Kroemer
DOI: https://doi.org/10.1007/978-3-319-62431-0
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing AG 2018
Hardcover ISBN: 978-3-319-62430-3Published: 05 January 2018
Softcover ISBN: 978-3-319-87310-7Published: 04 June 2019
eBook ISBN: 978-3-319-62431-0Published: 13 December 2017
Edition Number: 1
Number of Pages: X, 724
Number of Illustrations: 2 b/w illustrations, 131 illustrations in colour
Topics: Oncology, Immunology, Cancer Research