Overview
- Includes a foreword by the Nobel laureates J. Michael Bishop and Harold Varmus
- Casts new light on the role of viruses and genes in the etiology of human cancer
- Discusses the latest developments in HIV vaccine development
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 407)
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Table of contents (8 chapters)
Keywords
About this book
This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.
Editors and Affiliations
About the editors
Klaus Bister, PhD, is a Professor Emeritus of Biochemistry of University of Innsbruck, Austria, and a Professor Adjunct of The Scripps Research Institute, La Jolla, CA, USA Â
Bibliographic Information
Book Title: Viruses, Genes, and Cancer
Editors: Eric Hunter, Klaus Bister
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-319-61804-3
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017
Hardcover ISBN: 978-3-319-61803-6Published: 06 September 2017
Softcover ISBN: 978-3-319-87167-7Published: 11 August 2018
eBook ISBN: 978-3-319-61804-3Published: 25 August 2017
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: XIII, 221
Topics: Cancer Research, Virology