Imaging and Metabolism

1. Front Matter

   Pages i-xiii

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2. Basic Principles

   1. Front Matter

      Pages 1-1

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   2. Molecular Imaging and Molecular Imaging Technologies

      • Katja Haedicke, Susanne Kossatz, Thomas Reiner, Jan Grimm

      Pages 3-27

   3. A Topical Report on the Design Principles of Metabolism

      • Christopher J. Halbrook, Ho-Joon Lee, Lewis C. Cantley, Costas A. Lyssiotis

      Pages 29-44

3. Metabolic Imaging Approaches

   1. Front Matter

      Pages 45-45

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   2. Overview of Positron-Emission Tomography Tracers for Metabolic Imaging

      • Ephraim Parent, Jonathan McConathy

      Pages 47-80

   3. Introduction: MRI/MRS as Metabolic Imaging Tools

      • David Wilson, Michael Ohliger

      Pages 81-98

   4. Metabolic Imaging Approaches: Optical Imaging

      • Matthew A. Wall, Tiffany M. Heaster, Karissa Tilbury, Woo June Choi, Darren Roblyer, Ruikang Wang et al.

      Pages 99-126

4. Metabolic Diseases

   1. Front Matter

      Pages 127-127

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   2. Cancer Metabolism

      • Daniel R. Wahl, Sriram Venneti

      Pages 129-154

   3. Inflammation and Immune Metabolism

      • Carmen Paus, Derk Draper, Mangala Srinivas, Erik H. J. G. Aarntzen

      Pages 155-173

   4. Imaging in Diabetes

      • Liang Zhang, Greg M. Thurber

      Pages 175-197

   5. Brain Disorders

      • Vesselin Z. Miloushev, Ronald G. Blasberg

      Pages 199-222

   6. Fatty Liver Disease

      • Scott C. Beeman, Joel R. Garbow

      Pages 223-241

   7. Imaging Myocardial Metabolism

      • Robert J. Gropler, Craig R. Malloy

      Pages 243-279

   8. Other Metabolic Syndromes

      • Matthew T. Whitehead, Andrea L. Gropman

      Pages 281-324

5. Back Matter

   Pages 325-331

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This book presents advanced molecular imaging techniques used to assess metabolic function. Covering state-of-the art modalities, it discusses the evaluation of a wide range of diseases that have a metabolic component, including cancer, inflammatory conditions, diabetes, neurodegeneration, and cardiovascular disorders. Imaging provides a quantitative perspective to the assessment of metabolic function and complements genetic analysis of disorders related to disrupted metabolism. Organized into four parts, the book highlights basic principles in molecular imaging techniques; metabolic imaging approaches, including magnetic resonance imaging (MRI), single-photon emission computed tomography (SPECT), positron emission tomography (PET), and hybrid modalities; metabolic diseases; and future perspectives. Featuring contributions from leading authorities in radiology, oncology, cardiology, and neurology, Imaging and  Metabolism is a pioneering exploration of the role of imaging modalities in assessing the physiological status of abnormal cells and diagnosing disease.

• advanced molecular imaging techniques
• cancer
• cardiovascular disorders
• diabetes
• inflammatory conditions
• metabolic diseases
• metabolic function
• neurodegeneration
• Diagnostic Radiology

• Radiology, Memorial Sloan Kettering Cancer Center Radiology, NEW YORK, USA

  Jason S. Lewis, Kayvan R. Keshari

Jason S. Lewis, PhD Emily Tow Jackson Chair in Oncology,  Professor and Vice Chairman for Research Department of Radiology Memorial Sloan Kettering Cancer Center 1275 York Avenue New York, NY 10065, USA Kayvan R. Keshari, PhD Assistant Member and Laboratory Head Department of Radiology Molecular Pharmacology and Chemistry Program Memorial Sloan Kettering Cancer Center 1275 York Avenue New York, NY 10065, USA Jason Lewis, PhD, is the co-editor of Imaging and Visualization in the Modern Operating Room (978-1-4939-2325-0) and contributor to several Springer books; e.g., Strauss: Nuclear Oncology (978-0-387-48893-6).

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