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  • © 2017

Heart Failure

  • Comprehensive and state of the art overview of current and emerging heart failure treatments
  • Up to date information on treatment guidelines and clinical trials in heart failure
  • Authorships of worldwide heart failure experts from both academia and industry

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 243)

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eBook USD 219.00
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Softcover Book USD 279.99
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Hardcover Book USD 379.99
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  • Durable hardcover edition
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Table of contents (25 chapters)

  1. Front Matter

    Pages i-ix
  2. The Three-Decade Long Journey in Heart Failure Drug Development

    • Kelly S. Lewis, Javed Butler, Johann Bauersachs, Peter Sandner
    Pages 1-14
  3. Epidemiology of Heart Failure

    • Francesco Orso, Gianna Fabbri, Aldo Pietro Maggioni
    Pages 15-33
  4. Comorbidities in Heart Failure

    • Haye H. van der Wal, Vincent M. van Deursen, Peter van der Meer, Adriaan A. Voors
    Pages 35-66
  5. Biomarkers of Heart Failure with Preserved and Reduced Ejection Fraction

    • Michele Senni, Emilia D’Elia, Michele Emdin, Giuseppe Vergaro
    Pages 79-108
  6. Heart Failure Guidelines on Pharmacotherapy

    • Lampros Papadimitriou, Carine E. Hamo, Javed Butler
    Pages 109-129
  7. Sacubitril/Valsartan (LCZ696) in Heart Failure

    • Yasser Khder, Victor Shi, John J. V. McMurray, Martin P. Lefkowitz
    Pages 133-165
  8. Ivabradine

    • Michel Komajda
    Pages 167-175
  9. Partial Adenosine A1 Agonist in Heart Failure

    • Wilfried Dinh, Barbara Albrecht-Küpper, Mihai Gheorghiade, Adriaan A. Voors, Michael van der Laan, Hani N. Sabbah
    Pages 177-203
  10. New and Emerging Therapies and Targets: Beta-3 Agonists

    • Lauriane Y. M. Michel, Jean-Luc Balligand
    Pages 205-223
  11. Novel sGC Stimulators and sGC Activators for the Treatment of Heart Failure

    • Stefanie Breitenstein, Lothar Roessig, Peter Sandner, Kelly S. Lewis
    Pages 225-247
  12. Steroidal and Novel Non-steroidal Mineralocorticoid Receptor Antagonists in Heart Failure and Cardiorenal Diseases: Comparison at Bench and Bedside

    • Peter Kolkhof, Frederic Jaisser, So-Young Kim, Gerasimos Filippatos, Christina Nowack, Bertram Pitt
    Pages 271-305
  13. Vasopressin and Vasopressin Antagonists in Heart Failure

    • Julie K. Vishram-Nielsen, Finn Gustafsson
    Pages 307-328
  14. Platelet-Derived Growth Factor in Heart Failure

    • John Medamana, Richard A. Clark, Javed Butler
    Pages 355-369
  15. Wnt Signaling in Cardiac Remodeling and Heart Failure

    • Vasili Stylianidis, Kevin C. M. Hermans, W. Matthijs Blankesteijn
    Pages 371-393
  16. Gene Therapy in Heart Failure

    • Anthony S. Fargnoli, Michael G. Katz, Charles R. Bridges, Roger J. Hajjar
    Pages 395-421
  17. Noncoding RNAs in Heart Failure

    • Seema Dangwal, Katharina Schimmel, Ariana Foinquinos, Ke Xiao, Thomas Thum
    Pages 423-445

About this book

This special issue of the Handbook of Experimental Pharmacology on Heart Failure covers the entire spectrum of the field, from the current understanding and definitions of heart failure, to epidemiology and the importance of co-morbidities, clinical trial design and biomarkers, as well as imaging technologies. The main focus of this book is to review current and emerging heart failure therapies and potential targets for treatment.

Editors and Affiliations

  • Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover Klinik für Kardiologie und Angiologie, Hannover, Germany

    Johann Bauersachs

  • Heart Institute, Stony Brook University , Stony Brook, USA

    Javed Butler

  • Heart and Lung Diseases, Bayer Pharma Aktiengesellschaft Heart and Lung Diseases, Wuppertal, Germany

    Peter Sandner

Bibliographic Information

  • Book Title: Heart Failure

  • Editors: Johann Bauersachs, Javed Butler, Peter Sandner

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-319-59659-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-59658-7Published: 21 June 2017

  • Softcover ISBN: 978-3-319-86673-4Published: 12 May 2018

  • eBook ISBN: 978-3-319-59659-4Published: 09 June 2017

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: IX, 581

  • Number of Illustrations: 70 b/w illustrations, 30 illustrations in colour

  • Topics: Pharmacology/Toxicology, Cardiology, Human Physiology

Buy it now

Buying options

eBook USD 219.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 279.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 379.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access