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  • © 2017

Histamine and Histamine Receptors in Health and Disease

  • Authors will cover hot topics in the field.
  • Update on last HEP volume on histamine published 25 years ago.
  • Unique topics are combined a in novel way
  • Includes supplementary material: sn.pub/extras
  • Includes supplementary material: sn.pub/extras

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 241)

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eBook USD 189.00
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Softcover Book USD 249.99
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Hardcover Book USD 329.99
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Table of contents (17 chapters)

  1. Front Matter

    Pages i-viii
  2. Structural Analysis of the Histamine H1 Receptor

    • Mitsunori Shiroishi, Takuya Kobayashi
    Pages 21-30
  3. Histamine Release from Mast Cells and Basophils

    • Francesco Borriello, Raffaella Iannone, Gianni Marone
    Pages 121-139
  4. Histamine H2 Receptor in Blood Cells: A Suitable Target for the Treatment of Acute Myeloid Leukemia

    • Federico Monczor, Sabrina Copsel, Natalia Fernandez, Carlos Davio, Carina Shayo
    Pages 141-160
  5. Histamine H1 Receptor Gene Expression and Drug Action of Antihistamines

    • Hiroyuki Fukui, Hiroyuki Mizuguchi, Hisao Nemoto, Yoshiaki Kitamura, Yoshiki Kashiwada, Noriaki Takeda
    Pages 161-169
  6. Histamine Clearance Through Polyspecific Transporters in the Brain

    • Takeo Yoshikawa, Kazuhiko Yanai
    Pages 173-187
  7. Histamine Food Poisoning

    • Maria Schirone, Pierina Visciano, Rosanna Tofalo, Giovanna Suzzi
    Pages 217-235
  8. Regulation of the Cardiovascular System by Histamine

    • Yuichi Hattori, Kohshi Hattori, Naoyuki Matsuda
    Pages 239-258
  9. Role of the Histamine H3 Receptor in the Central Nervous System

    • Eberhard Schlicker, Markus Kathmann
    Pages 277-299
  10. Clinical Development of Histamine H4 Receptor Antagonists

    • Robin L. Thurmond, Jennifer Venable, Brad Savall, David La, Sandra Snook, Paul J. Dunford et al.
    Pages 301-320
  11. Allergy, Histamine and Antihistamines

    • Martin K. Church
    Pages 321-331
  12. Histamine and Histamine Receptors in Allergic Dermatitis

    • Hiroshi Ohtsu, Masahiro Seike
    Pages 333-345
  13. Back Matter

    Pages 361-363

About this book

This ​book provides a comprehensive overview on current histamine and histamine receptor research in context of human health and disease and reflect the multidisciplinary nature of the field. While the editors realize that it is almost impossible to cover the field completely within the constraints of a single HEP volume, nonetheless, all important aspects will be covered in one way or the other. An overarching introductory chapter will link the individual chapters and provide an overview on the field. This chapter will also link the book to the previous HEP volume on histamine receptors and the recent HEP volume on the pharmacology of itch. Great attention will be paid to complementation of existing literature while avoiding undue duplication. The book will cover new methods for analysis of histamine and histamine metabolites, development of methods for histamine receptor analysis, signal transduction, histamine release, regulation of immune cells by histamine, histamine metabolism and associated diseases, regulation of major organ systems by histamine and development of new drugs and experimental tools for the study of histamine receptors.

Editors and Affiliations

  • Department of Molecular and Medical Pharmacology, Graduate School of Medical and Pharmaceutical Sciences, University of Toyama, Toyama, Japan

    Yuichi Hattori

  • Institute of Pharmacology, Medical School of Hannover, Hannover, Germany

    Roland Seifert

Bibliographic Information

Buy it now

Buying options

eBook USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access