Editors:
Will thoroughly explain previously unconnected clinical date such as why mammography works better for women age 50-59 than for women age 40-49;
Will explore why adjuvant chemotherapy works best for premenopausal patients with positive lymph nodes and may also explain the racial disparity in outcome;
Focuses on post-operative inflammation and its role in metastatic relapse.
Includes supplementary material: sn.pub/extras
Includes supplementary material: sn.pub/extras
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Table of contents (11 chapters)
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Front Matter
About this book
The book will explain previously unconnected clinical data such as why mammography works better for women age 50-59 than it does for women age 40-49, why adjuvant chemotherapy works best for premenopausal patients with positive lymph nodes, and it may also explain the racial disparity in outcome. In particular, it points to the perioperative period when systemic inflammation persists for a week or so. This can lead to a variety of mechanisms whereby single cancer cells (perhaps from the marrow) begin division and angiogenesis of dormant avascular micrometastases occurs leading to early relapses.
With chapters presented from distinguished scientists and physicians in a variety of specialties that relate to and border the effects we present, this volume can be used as a reference for practicing physicians and as a jumping-off point for researchers to explore new therapeutic opportunities.
Editors and Affiliations
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Harvard TH Chan School of Public Health, Boston, USA
Michael W. Retsky
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Istituto Nazionale Tumori di Milano, Fondazione IRCCS, Milan, Italy
Romano Demicheli
About the editors
Romano Demicheli, MD, PhD, is Senior Researcher, Istituto Nazionale Tumori di Milano
Bibliographic Information
Book Title: Perioperative Inflammation as Triggering Origin of Metastasis Development
Editors: Michael W. Retsky, Romano Demicheli
DOI: https://doi.org/10.1007/978-3-319-57943-6
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2017
Hardcover ISBN: 978-3-319-57942-9Published: 07 July 2017
Softcover ISBN: 978-3-319-86289-7Published: 12 August 2018
eBook ISBN: 978-3-319-57943-6Published: 28 June 2017
Edition Number: 1
Number of Pages: XXIII, 236
Number of Illustrations: 10 b/w illustrations, 39 illustrations in colour
Topics: Cancer Research