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  • Book
  • © 2017

The Immunology of Cardiovascular Homeostasis and Pathology

  • Each chapter provides the fundamentals and new developments, to focus the book towards both the novice and the expert
  • Offers thorough insight into the rapidly emerging and growing field of cardiovascular immunology
  • Contributors comprise a good mix of immunologists and vascular biologists

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1003)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xii
  2. The Immune System in Tissue and Organ Homeostasis

    1. Front Matter

      Pages 1-1
  3. Immune Functions and Properties of Resident Cells in the Heart and Cardiovascular System

    1. Front Matter

      Pages 15-15
    2. Properties and Immune Function of Cardiac Fibroblasts

      • Milena B. Furtado, Muneer Hasham
      Pages 35-70
    3. Endothelial Cells

      • Caterina Sturtzel
      Pages 71-91
    4. The Role of Cardiac Tissue Macrophages in Homeostasis and Disease

      • Alexei Ilinykh, Alexander R. Pinto
      Pages 105-118
  4. The Immune System in Cardiovascular Pathology

    1. Front Matter

      Pages 119-119
    2. Atherosclerosis

      • Mohammed Shamim Rahman, Kevin Woollard
      Pages 121-144
    3. Immune-Mediated Heart Disease

      • Elena Generali, Marco Folci, Carlo Selmi, Piersandro Riboldi
      Pages 145-171
    4. Vasculitis in the Central Nervous System

      • Anastasia Bougea, Nikolaos Spantideas
      Pages 173-185
    5. Cardiac Autoimmunity: Myocarditis

      • William Bracamonte-Baran, Daniela ÄŒiháková
      Pages 187-221
  5. The Immune System in Repair and Regeneration After Myocardial Infarct

    1. Front Matter

      Pages 223-223
    2. Lymphocytes at the Heart of Wound Healing

      • Vânia Nunes-Silva, Stefan Frantz, Gustavo Campos Ramos
      Pages 225-250
  6. Back Matter

    Pages 273-283

About this book

Cardiovascular immunology is a newly emerging research area, investigating the crosstalk between the cardiovascular and the immune system. This crosstalk is evident through (1) crucial immunological capacities and functions of cardiovascular cell types, including cardiomyocytes, fibroblasts, endothelial cells, pericytes and cardiac resident macrophages, (2) the impact of aberrant immune function on the development of cardiovascular disease such as atherosclerosis, direct and indirect immune-mediated heart disease and vasculitis, and (3) the crucial role of the immune system in cardiac repair and regeneration.

The Immunology of Cardiovascular Homeostasis and Pathology covers all these aspects of cardiovascular immunology, starting with homeostatic immunological functions of traditional cardiovascular cell types, and moving then to the role of the immune system in cardiovascular pathology and to recent research into targeting the immune system to boost cardiac healing and regeneration.

Editors and Affiliations

  • Hammersmith Campus, Imperial College London National Heart and Lung Institute, London, United Kingdom

    Susanne Sattler, Teresa Kennedy-Lydon

About the editors

Susanne Sattler, National Heart and Lung Institute, Imperial College London

Teresa Kennedy-Lydon, National Heart and Lung Institute, Imperial College London

Bibliographic Information

  • Book Title: The Immunology of Cardiovascular Homeostasis and Pathology

  • Editors: Susanne Sattler, Teresa Kennedy-Lydon

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-319-57613-8

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017

  • Hardcover ISBN: 978-3-319-57611-4Published: 10 July 2017

  • Softcover ISBN: 978-3-319-86207-1Published: 02 August 2018

  • eBook ISBN: 978-3-319-57613-8Published: 30 June 2017

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XII, 283

  • Number of Illustrations: 2 b/w illustrations, 24 illustrations in colour

  • Topics: Immunology, Cardiology, Laboratory Medicine