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  • © 2017

Behavioral Neuroscience of Orexin/Hypocretin

  • Provides a timely discussion of how the neuropeptide orexin regulates behavior
  • Includes latest findings in this fast-moving field
  • Aims to capture a broad audience of basic scientists and clinicians

Part of the book series: Current Topics in Behavioral Neurosciences (CTBN, volume 33)

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eBook USD 169.00
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Softcover Book USD 219.99
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Table of contents (13 chapters)

  1. Front Matter

    Pages i-viii
  2. The Human Orexin/Hypocretin Receptor Crystal Structures

    • Jie Yin, Daniel M. Rosenbaum
    Pages 1-15
  3. Orexin/Hypocretin Signaling

    • Jyrki P. Kukkonen
    Pages 17-50
  4. The Hypocretin/Orexin Neuronal Networks in Zebrafish

    • Idan Elbaz, Talia Levitas-Djerbi, Lior Appelbaum
    Pages 75-92
  5. Hypocretins and Arousal

    • Shi-Bin Li, William J. Giardino, Luis de Lecea
    Pages 93-104
  6. Orexin OX2 Receptor Antagonists as Sleep Aids

    • Laura H. Jacobson, Sui Chen, Sanjida Mir, Daniel Hoyer
    Pages 105-136
  7. Roles for Orexin/Hypocretin in the Control of Energy Balance and Metabolism

    • Paulette B. Goforth, Martin G. Myers
    Pages 137-156
  8. Orexin and Central Modulation of Cardiovascular and Respiratory Function

    • Pascal Carrive, Tomoyuki Kuwaki
    Pages 157-196
  9. Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders

    • Morgan H. James, Erin J. Campbell, Christopher V. Dayas
    Pages 197-219
  10. The Role of Orexins/Hypocretins in Alcohol Use and Abuse

    • Leigh C. Walker, Andrew J. Lawrence
    Pages 221-246
  11. A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?

    • Morgan H. James, Stephen V. Mahler, David E. Moorman, Gary Aston-Jones
    Pages 247-281
  12. Hypocretin/Orexin and Plastic Adaptations Associated with Drug Abuse

    • Corey Baimel, Stephanie L. Borgland
    Pages 283-304
  13. Orexin and Alzheimer’s Disease

    • Claudio Liguori
    Pages 305-322

About this book

This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal states, critical for higher order functioning. From a clinical perspective, genetic polymorphisms in hypocretin/orexin and orexin receptors are implicated in a number of psychiatric disorders. In addition, advanced clinical trials are currently underway for orexin receptor antagonists in the treatment of insomnia and sleep disorders. We aim to capture a broad audience of basic scientists and clinicians.

Editors and Affiliations

  • Florey Institute of Neuroscience & Mental Health, Melbourne Brain Centre, University of Melbourne, Parkville, Australia

    Andrew J Lawrence

  • Dep Psychiatry & Behav Sciences, Stanford University, Stanford, USA

    Luis de Lecea

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access