Ultraviolet Light in Human Health, Diseases and Environment

1. Front Matter

   Pages i-xxiv

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2. Introduction, Historical Aspects and Sources of UV Light

   1. Front Matter

      Pages 1-1

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   2. History of UV Lamps, Types, and Their Applications

      • Shamim I. Ahmad, Luisa Christensen, Elma Baron

      Pages 3-11

3. UV Photoproducts, Damage to DNA and Mutagenesis

   1. Front Matter

      Pages 13-13

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   2. Ultraviolet Light Induced Generation of Reactive Oxygen Species

      • T. L. de Jager, A. E. Cockrell, S. S. Du Plessis

      Pages 15-23

4. UV Light and Human Diseases

   1. Front Matter

      Pages 25-25

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   2. UV-Induced Molecular Signaling Differences in Melanoma and Non-melanoma Skin Cancer

      • Feng Liu-Smith, Jinjing Jia, Yan Zheng

      Pages 27-40

   3. Xeroderma Pigmentosa Group A (XPA), Nucleotide Excision Repair and Regulation by ATR in Response to Ultraviolet Irradiation

      • Phillip R. Musich, Zhengke Li, Yue Zou

      Pages 41-54

   4. Impact of Ultraviolet Light on Vitiligo

      • Rasnik K. Singh

      Pages 55-60

   5. Polymorphous Light Eruption

      • Marcella Guarrera

      Pages 61-70

   6. Ultraviolet Radiations: Skin Defense-Damage Mechanism

      • Dheeraj Mohania, Shikha Chandel, Parveen Kumar, Vivek Verma, Kumar Digvijay, Deepika Tripathi et al.

      Pages 71-87

   7. Ultraviolet Photobiology in Dermatology

      • Luisa Christensen, Amanda Suggs, Elma Baron

      Pages 89-104

   8. Ultraviolet A-1 in Dermatological Diseases

      • Torello M. Lotti, Serena Gianfaldoni

      Pages 105-110

   9. Photodermatoses in the Pigmented Skin

      • Vinod Kumar Sharma, Kanika Sahni

      Pages 111-122

   10. Psycho-Neuro-Endocrine-Immunology: A Psychobiological Concept

       • Katlein França, Torello M. Lotti

       Pages 123-134

5. UV Light Benefits to Man

   1. Front Matter

      Pages 135-135

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   2. Ultraviolet B Radiation: The Vitamin D Connection

      • Michael F. Holick

      Pages 137-154

   3. Role of Vitamin D in Rheumatoid Arthritis

      • Mattia Bellan, Pier Paolo Sainaghi, Mario Pirisi

      Pages 155-168

   4. Asthma and Allergy “Epidemic” and the Role of Vitamin D Deficiency

      • Konstantinos Douros, Barbara Boutopoulou, Sotirios Fouzas, Ioanna Loukou

      Pages 169-183

   5. Vitamin D Metabolism and the Implications for Atherosclerosis

      • Amanda L. Bennett, Carl J. Lavie

      Pages 185-192

This book is about the roles and importance of Ultraviolet (UV) light from sun and from man-made UV lamps in our daily life, on health and diseases, also its application in sterilization and treatment. The key words are: reactive oxygen species, DNA damage, UV mutagenicity, skin cancers, polymorphous light eruption, Xeroderma pigmentosum, vitiligo, psoriasis, rheumatoid arthritis, diabetes mellitus, metabolic syndromes, cardiovascular diseases, dermatology, photobiology, photodermatosis, vitamin D synthesis, vitamin D efficiency, water sterilization, blood sterilization, phototherapies, skin tanning and UV dosimeter.

The book starts with introduction to UV light and the history of development of UV lamps and its applications. It then moves to describing the interaction of this light with biological components and the production of reactive oxygen species, their roles in cell signaling, cellular defense from foreign invaders, in mutagenesis leading to skin diseases includingvitiligo, polymorphous light eruption and various forms of skin cancer. Then it presents the synthesis and importance of UV light and diseases, induced due to the deficiency of vitamin D. Roles of UV light in sterilization, disinfection, phototherapies are depicted in the next part and finally use and abuse of UV light in tanning salon and the availability and importance of use of UV dosimeter are highlighted.

The three main focuses of this book are:
- Damage to biological systems by UV light leading to certain skin diseases; most importantly skin cancers.
- Importance of UV light in the in vivo synthesis of vitamin D when human bodies are exposed to it.
- Diseases caused due to the deficiency of vitamin D and the use of UV lamps in phototherapy and sterilization processes.

The editor has considerable experience in publishing medical books and has used it critically selecting the matters which will attract the readers from many areas of medical and non-medical fields.

It is hoped that the materials presented in this book will give great benefit and will stimulate both novice and expert researchers in the field. The book gives excellent overviews of the current status of research and pointers to the future research achievements. Clinicians, medical general practitioners, technicians and staff working in UV related industries and especially those working in tanning salon should benefit from the information presented in safe handling of this light.

 

• Skin Cancer
• Vitamin D
• Phototherapy
• Reactive oxygen species
• Ecological Balance

• Faculty of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom

  Shamim I. Ahmad

The editor has considerable experience and expertise to publish high volume books covering a wide range of chapters associated with the title of the books. Two good examples are the books (1) Diabetes: an old disease, a new insight and (2) Neurodegenerative diseases, both published by Springer. Chapter downloads of the Diabetes book during 2013 and 2014 have been 117, 280 and for the book on Neurodegenerative disease on March 13, 2012 there has been a total of 33,233 chapter downloads (later data not available). According to the publisher the second book was one of the top 25% most downloaded eBooks. The expectation is that this book on ultraviolet light will also catch the market and will be one of the best sellers of Springer publications. Attracting highly specialized and famous, in their field, scientists, their highly comprehensive inputs are the criteria that will attract readers as bees towards the flowers. Pooling up the chapter titles as wide and contributions of highly expertscientists and researchers are one of the key factors of the success of the books I am proposing.

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