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Epigenetics of Infectious Diseases

  • Book
  • © 2017

Overview

Editors:
  1. Walter Doerfler

    1. Institute for Clinical and Molecular Virology, University Erlangen-Nürnberg Medical School, Erlangen, Germany

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  2. Josep Casadesús

    1. Departamento de Genética, Universidad de Sevilla, Sevilla, Spain

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  • Broadens your understanding of patho-epigenetics of infectious disorders
  • First book on the mechanisms underlying epigenetic reprogramming associated with viral, bacterial and protozoan infections
  • From epigenetic mechanisms to functional analysis of disease development

Part of the book series: Epigenetics and Human Health (EHH)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-viii
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  2. DNA Methylation of Human Papillomavirus Genomes During Infection and Cancer Progression

    • Hans-Ulrich Bernard
    Pages 1-14

  3. Epigenetic Regulation of Gammaherpesviruses: A Focus on Kaposi’s Sarcoma-Associated Herpesvirus (KSHV/HHV-8)

    • Rosha Poudyal, Rolf Renne, Michael P. Kladde
    Pages 15-46

  4. Discoveries in Molecular Genetics with the Adenovirus 12 System: Integration of Viral DNA and Epigenetic Consequences

    • Walter Doerfler
    Pages 47-63

  5. Epigenetic Consequences of Epstein–Barr Virus Infection

    • Christine E. Birdwell, Krista Queen, Rona S. Scott
    Pages 65-87

  6. Epigenetic Programming by Microbial Pathogens and Impacts on Acute and Chronic Disease

    • Michael J. Mahan, Douglas M. Heithoff, Lucien Barnes V, Robert L. Sinsheimer
    Pages 89-112

  7. Cross Talk Between Bacteria and the Host Epigenetic Machinery

    • Hélène Bierne
    Pages 113-158

  8. Epigenetic Phase Variation in Bacterial Pathogens

    • Marjan W. van der Woude
    Pages 159-173

  9. Epigenetic Switching in the Human Fungal Pathogen Candida albicans

    • Han Du, Guanghua Huang
    Pages 175-187

  10. Modification of the Host Epigenome by Parasitic Protists

    • Inessa Gendlina, Natalie Silmon de Monerri, Kami Kim
    Pages 189-220

  11. Epigenetic Regulation in T. brucei: Changing Coats Is a Chance to Survive

    • Ana C. Pena, Francisco Aresta-Branco, Luísa M. Figueiredo
    Pages 221-241

  12. Epigenetics of Malaria Parasites

    • Evelien M. Bunnik, Karine G. Le Roch
    Pages 243-264

  13. Back Matter

    Pages 265-277
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Keywords

About this book

The present volume of Epigenetics and Human Health is devoted to the patho-epigenetics of viral and microbial infections, an exiting new field of disease-related epigenetic research. As recognized during the past years, epigenetic reprogramming of pathogen and host genome functions – the latter frequently induced by pathogens – plays an important role in many infectious processes. Beyond their immediate relevance for pathogen proliferation and obligatorily associated symptoms, such alterations frequently contribute to severe additional complications, such as the development of immunodeficiency, cancer and various chronic disorders. This holds in particular for epigenetic dysregulation of host gene expression induced by latent infections. The present book summarizes current knowledge of the mechanisms underlying epigenetic changes caused by viral, bacterial, fungal and protozoan infections and their impact on human health.

Editors and Affiliations

  • Institute for Clinical and Molecular Virology, University Erlangen-Nürnberg Medical School, Erlangen, Germany

    Walter Doerfler

  • Departamento de Genética, Universidad de Sevilla, Sevilla, Spain

    Josep Casadesús

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