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Computational Psychiatry

A Systems Biology Approach to the Epigenetics of Mental Disorders

Authors:

  • One of the first books that models mental function within sociocultural, socioeconomic, and environmental context

  • This volume applies the asymptotic limit theorems of information and control theories to construct a family of statistical models -- akin to but different from regression models – that can be used to analyze observational and empirical data in a field where such tools are sadly lacking

  • The systems biology approach, in addition, provides a philosophical context that is lacking in`brain only’ treatments of mental disorders which commit the ‘mereological fallacy’ of attributing to one part what are aspects of the whole: the full person embedded in socioculture and history

  • Includes supplementary material: sn.pub/extras

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xii
  2. Sleep, Psychopathology, and Culture

    • Rodrick Wallace
    Pages 105-128
  3. Embodied Cognition and Its Disorders

    • Rodrick Wallace
    Pages 129-152
  4. Tools for the Future: Hidden Symmetries

    • Rodrick Wallace
    Pages 153-165
  5. The Dynamics of Environmental Insult

    • Rodrick Wallace
    Pages 201-208
  6. Mathematical Appendix

    • Rodrick Wallace
    Pages 221-233
  7. Back Matter

    Pages 235-236

About this book

This book explores mental disorders from a uniquely evolutionary perspective. Although there have been many attempts to mathematically model neural processes and, to some extent, their dysfunction, there is very little literature that models mental function within a sociocultural, socioeconomic, and environmental context.

Addressing this gap in the extant literature, this book explores essential aspects of mental disorders, recognizing the ubiquitous role played by the exaptation of crosstalk between cognitive modules at many different scales and levels of organization, the missing heritability of complex diseases, and cultural epigenetics. Further, it introduces readers to valuable control theory tools that permit the exploration of the environmental induction of neurodevelopmental disorders, as well as the study of the synergism between culture, psychopathology and sleep disorders, offering a distinctively unique resource.

Authors and Affiliations

  • New York State Psychiatric Institute, New York, USA

    Rodrick Wallace

About the author

Rodrick Wallace, is a research scientist at the New York State Psychiatric Institute, and a professor at Columbia University. He received a B.S. in mathematics and a Ph.D. in physics from Columbia University. A recipient of an Investigator Award in Health Policy Research from The Robert Wood Johnson Foundation, he has also published the book “Gene Expression and Its Discontents” with his colleague Deborah Wallace. He has published many papers adapting quantitative methods from population, community and ecosystem ecology to the theoretical and empirical analysis of problems of public health and public order. 

Bibliographic Information

  • Book Title: Computational Psychiatry

  • Book Subtitle: A Systems Biology Approach to the Epigenetics of Mental Disorders

  • Authors: Rodrick Wallace

  • DOI: https://doi.org/10.1007/978-3-319-53910-2

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-53909-6Published: 03 May 2017

  • Softcover ISBN: 978-3-319-85273-7Published: 25 July 2018

  • eBook ISBN: 978-3-319-53910-2Published: 20 April 2017

  • Edition Number: 1

  • Number of Pages: XII, 236

  • Number of Illustrations: 31 b/w illustrations

  • Topics: Systems Biology, Human Genetics, Psychiatry

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access