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Blue Biotechnology

From Gene to Bioactive Product

  • Book
  • © 2017

Overview

Editors:
  1. Werner E. G. Müller

    1. ERC Advanced Investigator Group, Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

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  2. Heinz C. Schröder

    1. ERC Advanced Investigator Group, Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

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  3. Xiaohong Wang

    1. ERC Advanced Investigator Group, Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

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  • Describes the discovery of molecules from unexploited extreme marine environments
  • Presents and investigates new approaches in marine genomics
  • Written by leading experts in the fields of marine genomics/biotechnology
  • Includes supplementary material: sn.pub/extras

Part of the book series: Progress in Molecular and Subcellular Biology (PMSB, volume 55)

Part of the book sub series: Marine Molecular Biotechnology (MMB)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. 35 Years of Marine Natural Product Research in Sweden: Cool Molecules and Models from Cold Waters

    • Lars Bohlin, Paco Cárdenas, Anders Backlund, Ulf Göransson
    Pages 1-34

  3. Major Antimicrobial Representatives from Marine Sponges and/or Their Associated Bacteria

    • Fei He, Linh H. Mai, Johan Gardères, Amjad Hussain, Vesna Erakovic Haber, Marie-Lise Bourguet-Kondracki
    Pages 35-89

  4. Discovery and Development of Novel Drugs

    • Vesna Erakovic Haber, Radan Spaventi
    Pages 91-104

  5. Computer-Aided Drug Discovery from Marine Compounds: Identification of the Three-Dimensional Structural Features Responsible for Antimalarial Activity

    • Caterina Fattorusso, Marco Persico, Francesca Rondinelli, Nausicaa Orteca, Antonio Di Dato
    Pages 105-158

  6. Bluegenics: Bioactive Natural Products of Medicinal Relevance and Approaches to Their Diversification

    • Joseph S. Zarins-Tutt, Emily R. Abraham, Christopher S. Bailey, Rebecca J. M. Goss
    Pages 159-186

  7. New Target Sites for Treatment of Osteoporosis

    • Werner E. G. Müller, Xiaohong Wang, Heinz C. Schröder
    Pages 187-219

  8. Biocalcite and Carbonic Acid Activators

    • Xiaohong Wang, Meik Neufurth, Emad Tolba, Shunfeng Wang, Heinz C. Schröder, Werner E. G. Müller
    Pages 221-257

  9. Electrospinning of Bioactive Wound-Healing Nets

    • Heinz C. Schröder, Emad Tolba, Bärbel Diehl-Seifert, Xiaohong Wang, Werner E.G. Müller
    Pages 259-290

  10. Entotheonella Bacteria as Source of Sponge-Derived Natural Products: Opportunities for Biotechnological Production

    • Agneya Bhushan, Eike E. Peters, Jörn Piel
    Pages 291-314
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Keywords

About this book

This book describes the discovery of molecules from unexploited extreme marine environments, and presents new approaches in marine genomics. It combines the current state of knowledge in marine genomics and advanced natural products’ chemistry to pursue the sustainable production of novel secondary metabolites (lead compounds), as well as pharmacologically active peptides/proteins, with antimicrobial, neuroprotective, anti-osteoporotic, anti-protozoan/anti-plasmodial, anti-ageing and immune-modulating effects. Further, it employs molecular-biology-based approaches and advanced chemical techniques to obtain and to select candidate compounds for pre-clinical and clinical studies.

Editors and Affiliations

  • ERC Advanced Investigator Group, Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

    Werner E. G. Müller, Heinz C. Schröder, Xiaohong Wang

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