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  • Book
  • © 2017

The Actin Cytoskeleton and Bacterial Infection

  • Presents a comprehensive overview of the actin modifying actions of bacterial toxins
  • Bridges the gap between common knowledge, new findings and new concepts for therapeutic approaches
  • A valuable resource for microbiologists, cell biologists, and clinicians whose work involves infectious diseases
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 399)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
  2. Comparative Studies of Actin- and Rho-Specific ADP-Ribosylating Toxins: Insight from Structural Biology

    • Hideaki Tsuge, Toshiharu Tsurumura, Akiyuki Toda, Haruka Murata, Waraphan Toniti, Toru Yoshida
    Pages 69-86
  3. Pathogenic Mechanisms of Actin Cross-Linking Toxins: Peeling Away the Layers

    • Elena Kudryashova, David B. Heisler, Dmitri S. Kudryashov
    Pages 87-112
  4. Type III Secreted Virulence Factors Manipulating Signaling to Actin Dynamics

    • Theresia E. B. Stradal, Sonia C. P. Costa
    Pages 175-199
  5. Acting on Actin: Rac and Rho Played by Yersinia

    • Martin Aepfelbacher, Manuel Wolters
    Pages 201-220
  6. Bacterial Actins and Their Interactors

    • Pananghat Gayathri
    Pages 221-242

About this book

This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton.
In short, this volume provides an overview of the various tricks bacteria have evolved to “act on actin” in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases.

Editors and Affiliations

  • Institut für Anatomie, Abteilung für Anatomie und Molekulare Embryologie, Ruhr-Universität Bochum, Bochum, Germany

    Hans Georg Mannherz

About the editor

Hans Georg MannherzRuhr-Universität Bochum
Institut für Anatomie
Abteilung für Anatomie und molekulare Embryologie
e-mail: Hans.Mannherz@ruhr-uni-bochum.de



Bibliographic Information

  • Book Title: The Actin Cytoskeleton and Bacterial Infection

  • Editors: Hans Georg Mannherz

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-319-50047-8

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017

  • Hardcover ISBN: 978-3-319-50046-1Published: 13 February 2017

  • Softcover ISBN: 978-3-319-84305-6Published: 13 July 2018

  • eBook ISBN: 978-3-319-50047-8Published: 07 February 2017

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: X, 242

  • Topics: Medical Microbiology, Pharmacology/Toxicology

Buy it now

Buying options

eBook USD 139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access