Overview
- Provides readers with an up-to-date review of the design, structure and function of a representative selection of fibrous proteins in both health and disease
- Is an invaluable collection of topical reviews for established researchers and postgraduate students in the fields of protein chemistry, biochemistry and structural biophysics
- Written by recognized authorities in the field
- Gives a clear account of the current status of fibrous protein research and, in addition, establishes the basis for deciding the most appropriate directions for future activity, including the applications of protein engineering and the commercial exploitation of new biomaterials
Part of the book series: Subcellular Biochemistry (SCBI, volume 82)
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Table of contents (18 chapters)
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Front Matter
Keywords
About this book
This book provides the readers with an up-to-date review of the design, structure and function of a representative selection of fibrous proteins in both health and disease. The importance of the α-helical coiled coil, a conformational motif based on the heptad repeat in the amino acid sequence of all α-fibrous proteins (and parts of some globular proteins) is underlined by three Chapters devoted to its design, structure, function and topology. Specific proteins covered in the text and which depend on the coiled coil for their structure and function, include the intermediate filament proteins, tropomyosin, myosin, paramyosin, fibrin and members of the spectrin superfamily. Also described are fibrous proteins based on the β-pleated sheet and collagen conformations. Recombinant structural proteins, especially of silk and collagen, are discussed in the context of developing new biomaterials with varied applications.
Established researchers and postgraduate students in the fields of protein chemistry, biochemistry and structural biophysics will find Fibrous Proteins: Structures and Mechanisms to be an invaluable collection of topical reviews that describe the basic advances made in the field of fibrous proteins over the past decade. This book, written by recognized authorities in the field, provides a clear account of the current status of fibrous protein research and, in addition, establishes the basis for deciding the most appropriate directions for future activity, including the applications of protein engineering and the commercial exploitation of new biomaterials.
Editors and Affiliations
Bibliographic Information
Book Title: Fibrous Proteins: Structures and Mechanisms
Editors: David A.D. Parry, John M. Squire
Series Title: Subcellular Biochemistry
DOI: https://doi.org/10.1007/978-3-319-49674-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2017
Hardcover ISBN: 978-3-319-49672-6Published: 25 January 2017
Softcover ISBN: 978-3-319-84211-0Published: 15 July 2018
eBook ISBN: 978-3-319-49674-0Published: 18 January 2017
Series ISSN: 0306-0225
Series E-ISSN: 2542-8810
Edition Number: 1
Number of Pages: VIII, 629
Number of Illustrations: 31 b/w illustrations, 123 illustrations in colour
Topics: Protein Science, Gene Expression, Biological and Medical Physics, Biophysics