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Drug Resistance in Bacteria, Fungi, Malaria, and Cancer

  • First book to give an overview on drug resistance spanning from microbes to primates
  • Gives comprehensive insights in mechanisms of emergence of drug resistance
  • Gives an outlook on the future of drug discovery

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xiv
  2. Emerging Themes in Drug Resistance

    • Gunjan Arora, Ankur Kulshreshtha, Kriti Arora, Puneet Talwar, Rishi Raj, Gurpreet Grewal et al.
    Pages 1-24
  3. Molecular Mechanism of Drug Resistance

    • Shilpa Ray, Susmita Das, Mrutyunjay Suar
    Pages 47-110
  4. Functional Roles of Highly Conserved Amino Acid Sequence Motifs A and C in Solute Transporters of the Major Facilitator Superfamily

    • Prathusha Kakarla, Ranjana KC, Ugina Shrestha, Indrika Ranaweera, Mun Mun Mukherjee, T. Mark Willmon et al.
    Pages 111-140
  5. How Pathogens Survive Drug Pressure?

    • Brijendra Kumar Tiwari, Gunjan Kak, Deepika Sharma, Krishnamurthy Natarajan
    Pages 141-159
  6. Functional Diversity and Applications of Mobile Group II Introns

    • Bhagwan Rekadwad, Juan M. Gonzalez, Chandrahasya N. Khobragade
    Pages 161-169
  7. Bacterial Resistance Against Antibiotics

    • Anil Kumar, Nikita Chordia
    Pages 171-192
  8. Drug-Resistant Tuberculosis

    • Lili Liang, Yun Ma, Xin liu, Yamin Lv
    Pages 193-208
  9. Implications of Chromosomal Mutations for Mycobacterial Drug Resistance

    • Gail E. Louw, Samantha L. Sampson
    Pages 233-262
  10. Role of External and Environmental Factors in Drug Resistance Emergence: Gut Microbiota

    • Daniel Ryan, Sangeeta Jaiswal, Mrutyunjay Suar
    Pages 287-305
  11. Tackling the Antibiotic Resistance: The “Gut” Feeling

    • Richa Misra, Richa Virmani, Darshan Dhakan, Abhijit Maji
    Pages 325-338
  12. In Silico Analytical Tools for Phylogenetic and Functional Bacterial Genomics

    • Vipin Chandra Kalia, Ravi Kumar, Shikha Koul
    Pages 339-355
  13. Exploiting Bacterial Genomes to Develop Biomarkers for Identification

    • Ravi Kumar, Shikha Koul, Vipin Chandra Kalia
    Pages 357-370
  14. Current Antifungal Therapy and Drug Resistance Mechanisms in Dermatophytes

    • Pawan Kumar, Chitra Latka, Bhupesh Taneja
    Pages 371-385
  15. Human Fungal Pathogens and Drug Resistance Against Azole Drugs

    • Preetida J. Bhetariya, Neha Sharma, Pragati Singh, Priyanka Tripathi, Santosh K. Upadhyay, Poonam Gautam
    Pages 387-428
  16. Drug Resistance in Malaria

    • Santosh C. M. Kumar
    Pages 429-447

About this book

This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.
Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way.

Editors and Affiliations

  • CSIR - Institute of Genomics and Integrative Biology, Delhi, India

    Gunjan Arora, Vipin Chandra Kalia

  • National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA

    Andaleeb Sajid

About the editors

Dr. Vipin Chandra Kalia is presently working as Chief Scientist, and is the Deputy Director, at Microbial Biotechnology and Genomics, CSIR-Institute of Genomics and Integrative Biology, Delhi. He is a Professor, AcSIR, who obtained his M.Sc. and Ph.D. in Genetics, from Indian Agricultural Research Institute, New Delhi. He has been elected as: (1) Fellow of the National Academy of Sciences (FNASc), (2) Fellow of the National Academy of Agricultural Sciences (FNAAS), and (3) Fellow of the Association of Microbiologists of India (FAMI). His main areas of research are Microbial biodiversity, Bioenergy, Biopolymers, Genomics, Microbial evolution, Quorum sensing, Quorum quenching, Drug discovery and Antimicrobials. He has published 99 papers in Scientific journals such as (1) Nature Biotechnology, (2) Biotechnology Advances, (3) Trends in Biotechnology, (4) Annual Review of Microbiology, (5) Critical Reviews in Microbiology, (6) Bioresource Technology, (7) PLoS ONE, (8) BMC Genomics, (9) International Journal of Hydrogen Energy, and (10) Gene. He has authored 14 book chapters. His works have been cited 3267 times with an h index of 31 and an i10 index of 59. He has Edited 3 books: (i) Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight (2015), (ii) Microbial Factories   Vol.  1: Biofuels, Waste treatment (2015) and (iii) Microbial Factories   Vol. 2:  Biodiversity, Biopolymers, Bioactive Molecules (2015). He is presently the Editor-in-Chief of the Indian Journal of Microbiology and editor of: (1) Journal of Microbiology & Biotechnology (Korea), (2) International Scholarly Res. Network Renewable Energy, (3) Dataset Papers in Microbiology, and (4) PLoS ONE. He is a life member of the following Scientific societies: (1) Society of Biological Chemists of India (2) Society for Plant Biochemistry and Biotechnology, India; (3) Association of Microbiologists of India; (4) Indian Science Congress Association; (5) BioEnergy Society of India, and (6) the Biotech Research Society of India (BRSI). He is also a member of the American Society for Microbiology.

Bibliographic Information

  • Book Title: Drug Resistance in Bacteria, Fungi, Malaria, and Cancer

  • Editors: Gunjan Arora, Andaleeb Sajid, Vipin Chandra Kalia

  • DOI: https://doi.org/10.1007/978-3-319-48683-3

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2017

  • Hardcover ISBN: 978-3-319-48682-6Published: 29 March 2017

  • Softcover ISBN: 978-3-319-83992-9Published: 20 July 2018

  • eBook ISBN: 978-3-319-48683-3Published: 21 March 2017

  • Edition Number: 1

  • Number of Pages: XIV, 630

  • Number of Illustrations: 15 b/w illustrations, 49 illustrations in colour

  • Topics: Drug Resistance, Cell Biology, Cancer Research, Bacteriology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access