Overview
Presents cancer biomarkers for noninvasive diagnosis of 18 different body fluids
Shows prosprectives for a coordinated validation of cancer biomarkers by industries, regulatory bodies, and academics for clinical translation
Presents opportunities for cancer personalized medicine ?
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Table of contents (18 chapters)
Keywords
About this book
This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry.
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About the author
Bibliographic Information
Book Title: Cancer Biomarkers in Body Fluids
Book Subtitle: Biomarkers in Circulation
Authors: Gabriel D. Dakubo
DOI: https://doi.org/10.1007/978-3-319-48360-3
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2017
Hardcover ISBN: 978-3-319-48359-7Published: 16 December 2016
Softcover ISBN: 978-3-319-83921-9Published: 05 July 2018
eBook ISBN: 978-3-319-48360-3Published: 23 November 2016
Edition Number: 1
Number of Pages: XIX, 509
Number of Illustrations: 20 illustrations in colour
Topics: Human Genetics, Oncology, Cancer Research