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  • Book
  • © 2016

Immunotherapy of Melanoma

  • Carefully written chapters useful for both basic and advanced oncologists and/or immunologists

  • Detailed and at the same time not-too-boring presentation of information on melanoma and immunotherapy

  • Over 1200 references (majority of which are available online)

  • Information on more than 150 clinical trials

  • Presentation of important information in the form synopsis in every chapter

  • Includes supplementary material: sn.pub/extras

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xi
  2. Melanoma

    1. Front Matter

      Pages 1-1
    2. Melanoma—Introduction, History and Epidemiology

      • Anand Rotte, Madhuri Bhandaru
      Pages 3-20
    3. Melanoma—Diagnosis, Subtypes and AJCC Stages

      • Anand Rotte, Madhuri Bhandaru
      Pages 21-47
    4. Etiology

      • Anand Rotte, Madhuri Bhandaru
      Pages 49-77
    5. Melanoma—Treatment

      • Anand Rotte, Madhuri Bhandaru
      Pages 79-109
  3. Tumor Immunology

    1. Front Matter

      Pages 111-111
    2. Overview of Immune System

      • Anand Rotte, Madhuri Bhandaru
      Pages 113-142
    3. Dendritic Cells

      • Anand Rotte, Madhuri Bhandaru
      Pages 143-166
    4. T-Lymphocytes

      • Anand Rotte, Madhuri Bhandaru
      Pages 167-198
    5. Mechanisms of Immune Evasion by Cancer

      • Anand Rotte, Madhuri Bhandaru
      Pages 199-232
  4. Immune Based Drugs Approved for Treatment of Melanoma

    1. Front Matter

      Pages 233-233
    2. Interferon-α2b

      • Anand Rotte, Madhuri Bhandaru
      Pages 235-256
    3. Interleukin-2

      • Anand Rotte, Madhuri Bhandaru
      Pages 257-273
    4. Ipilimumab

      • Anand Rotte, Madhuri Bhandaru
      Pages 275-296
    5. Nivolumab

      • Anand Rotte, Madhuri Bhandaru
      Pages 297-317
    6. Pembrolizumab

      • Anand Rotte, Madhuri Bhandaru
      Pages 319-332
    7. Talimogene Laherparepvec

      • Anand Rotte, Madhuri Bhandaru
      Pages 333-347
  5. Ongoing Research

    1. Front Matter

      Pages 349-349
    2. Promising Immunotherapeutic Approaches in Clinical Trials

      • Anand Rotte, Madhuri Bhandaru
      Pages 351-416

About this book

This book focusses on the different types of immunotherapeutics that are currently being used and developed for the treatment of melanoma. In recent years, immunotherapy has revolutionized the treatment of metastatic melanoma and other types of cancer.

Discussing treatment options for melanoma and the success of immunotherapy along with the challenges of immunotherapy, this book covers epidemiology, susceptibility genes, and treatment recommendations from Society for Immunotherapy of Cancer, as well as immune based therapies such as aldesleukin, Intron-A, Sylatron, Yervoy, Opdivo, Keytruda, Imlygic, DC vaccines and adoptive cell therapy.

The detailed information included on the key immune cells involved in anti-tumor immune response and immune-inhibitory mechanisms in tumor microenvironment will aid the understanding of tumor immunology. Both academic as well as industry-based researchers, developing novel anti-cancer therapies, will also benefit from the details of promising molecular targets and immunotherapeutic strategies under investigation.

With 132 illustrations including synopsis tables for important information, over 1200 references (majority of which are openly accessible) and details of more than 150 ongoing clinical trials, this book is a valuable source of information for health care providers as well as cancer biologists interested in learning about melanoma and the significant advances made by immunotherapy. 

Authors and Affiliations

  • Dermatology & Skin Science, Faculty of Medicine, University of British Columbia, Vancouver, Canada

    Anand Rotte

  • Dermatology & Skin Science, Faculty of Medicine, University of British Columbia , Vancouver, Canada

    Madhuri Bhandaru

Bibliographic Information

  • Book Title: Immunotherapy of Melanoma

  • Authors: Anand Rotte, Madhuri Bhandaru

  • DOI: https://doi.org/10.1007/978-3-319-48066-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2016

  • Hardcover ISBN: 978-3-319-48065-7Published: 04 January 2017

  • Softcover ISBN: 978-3-319-83890-8Published: 07 July 2018

  • eBook ISBN: 978-3-319-48066-4Published: 19 December 2016

  • Edition Number: 1

  • Number of Pages: XI, 434

  • Number of Illustrations: 7 b/w illustrations, 52 illustrations in colour

  • Topics: Cancer Research, Oncology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access