Opioid Dependence

1. Front Matter

   Pages i-xv

   PDF

2. Part I

   1. Front Matter

      Pages 1-1

      PDF

   2. An Epidemiologic Perspective

      • Heath B. McAnally

      Pages 3-19

3. Part II

   1. Front Matter

      Pages 21-21

      PDF

   2. Understanding the Agent, Part I: Opioid Biology and Basic Pharmacology

      • Heath B. McAnally

      Pages 23-47

   3. Understanding the Agent, Part II: Adverse Effects

      • Heath B. McAnally

      Pages 49-71

   4. Understanding the Agent, Part III: Specific Drugs

      • Heath B. McAnally

      Pages 73-97

   5. Attenuating the Agent: Reducing Opioid “Virulence”

      • Heath B. McAnally

      Pages 99-118

4. Part III

   1. Front Matter

      Pages 119-119

      PDF

   2. Best Practices Education, Part I: Pain Physiology, Psychology, and Alternatives to Opioids

      • Heath B. McAnally

      Pages 121-148

   3. Best Practices Education, Part II: Evidence for and Against Opioid Therapy

      • Heath B. McAnally

      Pages 149-173

   4. Best Practices Education, Part III: Regulatory and Advisory Issues Related to Opioid Therapy for Pain

      • Heath B. McAnally

      Pages 175-203

5. Part IV

   1. Front Matter

      Pages 205-205

      PDF

   2. Addressing Host Factors: Overview of Dependence and Addiction

      • Heath B. McAnally

      Pages 207-232

   3. Opioid Dependence Risk Factors and Risk Assessment

      • Heath B. McAnally

      Pages 233-264

   4. Addressing Host Factors: Primary, Secondary, and Tertiary Prevention of Opioid Dependence

      • Heath B. McAnally

      Pages 265-290

6. Back Matter

   Pages 291-301

   PDF

The book begins with a public health/epidemiologic examination of the situation, with a systematic view of the problem based on classic (infectious disease) epidemiologic principles applied to this behavioral health issue. This application is expanded to take into account the fact that unlike most epidemics in our species’ history, a unique factor that must be accounted for in any public health analysis is that the host (opioid-dependent/misusing patient) is generally not under sufficiently strong motivation to avoid the disease.  The introduction concludes with a survey of recent containment approaches, categorized epidemiologically by target (agent, vector, host.)


The remainder of the book is organized according to this framework, addressing agent, vector/transmission and host, respectively.  Sections Three and Four comprise the major focus of the book, and are dedicated primarily to practical education for primary care providers in preventing opioid use disorder, and overcoming it after the fact. 

• Opioid
• Dependence
• Abuse
• Addiction
• Risk management

“The book is intended for all healthcare professionals, specifically prescribers including physicians, nurse practitioners, advanced practice nurses, and residents who treat patients with acute and chronic pain. It is also appropriate for nonprescribers and trainees in healthcare settings managing these patient populations. … This book covers the increasingly problematic opiate abuse problem from an epidemiological perspective.” (Michael Easton, Doody's Book Reviews, March, 2018)

“This is quite of an intro into mind puzzling theme as opioid dependence which caught attention of all medical professionals prescribing opioid medications. … I would like to conclude that authors gave great insight into scientificviews of opioid dependence and medication assisted therapy but emphasized that it requires much more than this for accomplishing recovery from opioid dependence.” (Marijana Batković, Alcoholism and Psychiatry Research, Vol. 53 (2). 2017)

• Northern Anesthesia & Pain Medicine, LLC, Eagle River, USA

  Heath B. McAnally

Heath McAnally, MD, MSPH

Medical Director

Northern Anesthesia & Pain Medicine, LLC

Eagle River, AK, USA

 

Clinical Instructor

University of Washington School of Medicine

WWAMI Program

Anchorage, AK, USA

Policies and ethics