Editors:
- Provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies.
- Offers organ system–based summaries of spontaneous pathology and common responses to xenobiotics.
- Complements the information provided in Immunopathology in Toxicology and Drug Development: Volume 1, Immunobiology, Investigative Techniques, and Special Studies.
- Includes supplementary material: sn.pub/extras
Part of the book series: Molecular and Integrative Toxicology (MOLECUL)
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Table of contents (15 chapters)
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Front Matter
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Back Matter
About this book
This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide organ system–based summaries of spontaneous pathology and common responses to xenobiotics. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 1, Immunobiology, Investigative Techniques, and Special Studies, offers an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays.
These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects ofdrug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system.
Reviews
Editors and Affiliations
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Charles River Laboratories, Inc., Durham, USA
George A. Parker
About the editor
George A. Parker, a leading expert in the field of toxicologic pathology, is currently a Senior Scientific Director, Global Pathology, at Charles River Laboratories. Dr. Parker is a graduate of Auburn University College of Veterinary Medicine and completed a residency program in veterinary pathology at the Armed Forces Institute of Pathology, as well as a Ph.D. program in molecular and cellular immunology at the University of Medicine and Dentistry of New Jersey. He is a board-certified pathologist and toxicologist as well as a fellow of the distinguished International Academy of Toxicologic Pathology. He has more than 35 years of experience in the field of toxicologic pathology, with an emphasis on the nonclinical safety assessment of drugs, agricultural chemicals, and industrial chemicals. Dr. Parker’s areas of specific expertise include immunopathology, toxicologic pathology of juvenile animals, and radiation pathology.
Bibliographic Information
Book Title: Immunopathology in Toxicology and Drug Development
Book Subtitle: Volume 2, Organ Systems
Editors: George A. Parker
Series Title: Molecular and Integrative Toxicology
DOI: https://doi.org/10.1007/978-3-319-47385-7
Publisher: Humana Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017
Hardcover ISBN: 978-3-319-47384-0Published: 26 April 2017
Softcover ISBN: 978-3-319-83726-0Published: 07 August 2018
eBook ISBN: 978-3-319-47385-7Published: 27 March 2017
Series ISSN: 2168-4219
Series E-ISSN: 2168-4235
Edition Number: 1
Number of Pages: XXII, 826
Number of Illustrations: 5 b/w illustrations, 250 illustrations in colour
Topics: Pathology, Immunology, Pharmaceutical Sciences/Technology, Medical Biochemistry