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Resistance to Targeted Therapies Against Adult Brain Cancers

  • Book
  • © 2016

Overview

  • This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumours
  • This volume will prove as a highly relevant, detailed and up-to-date account of the research and findings in the field of brain cancer research and resistance to currently developed targeted therapies
  • This volume will also contain information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance and state-of-the-art imaging of targeted therapies
  • Includes supplementary material: sn.pub/extras

Part of the book series: Resistance to Targeted Anti-Cancer Therapeutics (RTACT)

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Table of contents (11 chapters)

Keywords

About this book

This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for more efficient targeted drug delivery in all forms of brain cancer treatment. The volume will include information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance, and state-of-the-art imaging of targeted therapies.

Reviews

“This is a complete monograph on the molecular and cell biology of 'brain tumors' resistant mechanisms. The book discusses chemotherapy and radiotherapy of brain malignancies including gliomas, ependynomas, and meningiomas. … I highly recommend this book as a reference and research tool for neurosurgeons, oncologists, neurologists, residents, and students.” (Joseph Grenier, Amazon.de, May, 2018)

Editors and Affiliations

  • Centre for Systems Medicine, Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland

    Amanda Tivnan

About the editor

Amanda Tivnan, PhD, is Senior Postdoctoral Research Fellow, Department of Physiology and Medical Physics, The Royal College of Surgeons, Dublin, Ireland.

Bibliographic Information

  • Book Title: Resistance to Targeted Therapies Against Adult Brain Cancers

  • Editors: Amanda Tivnan

  • Series Title: Resistance to Targeted Anti-Cancer Therapeutics

  • DOI: https://doi.org/10.1007/978-3-319-46505-0

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2016

  • Hardcover ISBN: 978-3-319-46504-3Published: 16 December 2016

  • Softcover ISBN: 978-3-319-83531-0Published: 04 July 2018

  • eBook ISBN: 978-3-319-46505-0Published: 26 November 2016

  • Series ISSN: 2196-5501

  • Series E-ISSN: 2196-551X

  • Edition Number: 1

  • Number of Pages: XVI, 260

  • Number of Illustrations: 3 b/w illustrations, 16 illustrations in colour

  • Topics: Cancer Research

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