Overview
- Focuses on recent therapeutic applications and future potential for drug discovery
- Bench-to-bedside" translational approach
- Explores different perspectives from various fields of study including medical medicinal chemistry, molecular biology, physiology, and preclinical and clinical pharmacology
- Explores specific diseases and disorders in which GABAB receptors have been implicated recently
Part of the book series: The Receptors (REC, volume 29)
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Table of contents (19 chapters)
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Front Matter
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Molecular Biology, Biochemistry, & Physiology
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Front Matter
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Pharmacology
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Front Matter
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Keywords
About this book
An up-to-date comprehensive overview of the GABA B receptor system with a particular focus on the most recent therapeutic applications and potential. This receptor system has recently been implicated in several diseases and disorders including gastroesophageal reflux disease, epilepsy, mood disorders, depression, and alcohol and substance use disorder. The authors, leading researchers in the field, explore a number of approaches, including medicinal chemistry, molecular biology, physiology, and preclinical and clinical pharmacology. This overview provides a translational perspective on the potential of the GABA B receptor pharmacology.
Editors and Affiliations
About the editor
Giancarlo Colombo is a researcher at the Neuroscience Institute, Section of Cagliari, National Research Council of Italy. He has previously worked at the Laboratory of Physiologic and Pharmacologic Studies, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD, USA, and the Department of Physiology and Pharmacology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC, USA.
His research interest is primarily on neurobiology and pharmacology of alcohol use disorder, with focus on the role of GABAB receptor in the control of multiple alcohol-related behaviors and the development of GABAB receptor ligands as possible pharmacotherapies for alcohol use disorder.
He has published approximately 200 papers in peer-reviewed journals and about 20 book chapters. He serves on the editorial board of the journals Alcohol and Alcohol and Alcoholism.Bibliographic Information
Book Title: GABAB Receptor
Editors: Giancarlo Colombo
Series Title: The Receptors
DOI: https://doi.org/10.1007/978-3-319-46044-4
Publisher: Humana Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-46042-0Published: 28 December 2016
Softcover ISBN: 978-3-319-83428-3Published: 14 June 2018
eBook ISBN: 978-3-319-46044-4Published: 19 December 2016
Series ISSN: 1048-6909
Series E-ISSN: 2524-6488
Edition Number: 1
Number of Pages: XX, 385
Number of Illustrations: 45 b/w illustrations, 19 illustrations in colour
Topics: Neurosciences, Neurology